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杂质
≤20 ppm heavy metals (verfied on random samples only)
灼烧残渣
≤3.0%
缺失
≤5% loss on drying
pH值(酸碱度)
5.0-8.0 (15% in H2O)
粘度
150-450 mPa.s, 20 % in solution(23 °C) (RVT, SP 2/100 RPM)
酯化值
50‑115 mg KOH/g
适用性
complies for Infrared spectrum
应用
Kollicoat Protect is a ready-to-use moisture barrier system for use in combination with pigments. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
分析说明
residual solvents (GLC-HS)
1,4 dioxane ≤380 ppm, ethylene glykol ≤620 ppm, vinyl acetate ≤100 ppm, methyl acetatea ≤1000 ppm, methanol ≤3000 ppm, acetic acid ≤15000 ppm
1,4 dioxane ≤380 ppm, ethylene glykol ≤620 ppm, vinyl acetate ≤100 ppm, methyl acetatea ≤1000 ppm, methanol ≤3000 ppm, acetic acid ≤15000 ppm
法律信息
Kollicoat is a registered trademark of BASF SE
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Effect of water-soluble polymers on the physical stability of aqueous polymeric dispersions and their implications on the drug release from coated pellets.
Dashevsky A, Ahmed AR, et al.
Drug Devel. Ind. Pharm., 36, 152-160 (2010)
New insight into modified release pellets - Internal structure and drug release mechanism.
Ensslin S, Moll KP, Paulus K, Mader K.
J. Controlled Release, 128, 149-156 (2008)
Sandra Strübing et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 66(1), 113-119 (2006-11-15)
The objective of this study was to receive detailed information on the mechanism of drug release from polyvinyl acetate (PVAc)/polyvinyl alcohol-polyethylene glycol graft copolymer (PVA-PEG) coated Propranolol HCl and Theophylline tablets. For this purpose the coating composition (PVAc/PVA-PEG: 90/10 and
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