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Merck
CN

39286

Sigma-Aldrich

羟基司替丁双(甲磺酸酯)

suitable for fluorescence, ≥96.0% (HPLC)

别名:

2-羟基二苯乙烯-4,4′-二羧氨基脒双(甲磺酸), 氟金, 2-羟基二苯乙烯-4,4′-二羧氨基脒双, 氟金

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About This Item

经验公式(希尔记法):
C18H24N4O7S2
分子量:
472.54
MDL编号:
UNSPSC代码:
41116100
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥96.0% (HPLC)

形式

powder

荧光

λex 318 nm; λem 560 nm in TBE Buffer

适用性

suitable for fluorescence

储存温度

2-8°C

SMILES字符串

CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N

InChI

1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;

InChI key

YGNSQKCULHSJDC-HFPMQDOPSA-N

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一般描述

羟基苯胺双(甲磺酸),又称荧光金,是一种逆行荧光示踪剂。在化学上,羟基苯胺是一种弱碱,可以其不带电的形式穿过细胞膜。

羟基苯胺双(甲磺酸)的部分性质包括:

  • 强烈的荧光反应。
  • 广泛树突填充。
  • 较高的抗褪色性。
  • 未受损纤维无法吸收。
  • 标记细胞不扩散。
  • 与其他神经组织化学技术高度兼容。

应用

羟基苯胺双(甲磺酸)或荧光金(FG)可用于标记神经元,并研究听力损失的早期影响。它可用于通过标记细胞来研究CNS内广泛轴突投射的形态学特征。
羟芪巴脒(甲磺酸)是一种荧光逆行示踪剂(轴突转运),在显微解剖学研究中用于神经定位。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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L Zhang et al.
Neuroscience, 228, 139-162 (2012-10-23)
The neuropeptide arginine vasopressin (AVP) exerts a modulatory role on hippocampal excitability through vasopressin V(1A) and V(1B) receptors. However, the origin and mode of termination of the AVP innervation of the hippocampus remain unknown. We have used light and electron
Tímea Bácskai et al.
Brain structure & function, 219(1), 303-321 (2013-01-05)
We have mapped the motor neurons (MNs) supplying the major hindlimb muscles of transgenic (C57/BL6J-ChAT-EGFP) and wild-type (C57/BL6J) mice. The fluorescent retrograde tracer Fluoro-Gold was injected into 19 hindlimb muscles. Consecutive transverse spinal cord sections were harvested, the MNs counted
M W Wessendorf
Brain research, 553(1), 135-148 (1991-07-05)
Determining the mechanism by which fluorescent retrograde neuronal tracers are taken up requires knowledge of their composition. It has been claimed that Fluoro-Gold, a retrogradely transported fluorescent neuronal tracer, is 2-hydroxy-4,4'-diamidinostilbene (hydroxystilbamidine), an amidine antibiotic. However, this appears questionable, since
N Kuwabara
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 87(6), 413-422 (2012-06-21)
A method is described for studying the morphological features of extensive axonal projections within the central nervous system of the gerbil, Meriones anguiculatus. Potentially long descending axonal projections between the auditory thalamus and lower brainstem were used as a model.
Lijie Chen et al.
Experimental and therapeutic medicine, 4(5), 844-848 (2012-12-12)
Understanding the microanatomy of the facial nerve is vital to functional restoration of facial nerve injury. This study aimed to locate the spatial orientation of five branches in the extratemporal trunk of the rat facial nerve (ETFN). Fifteen adult Sprague-Dawley

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