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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP212, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
2
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
EP212, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (386R-14)
vial of 0.5 mL concentrate (386R-15)
bottle of 1.0 mL predilute (386R-17)
vial of 1.0 mL concentrate (386R-16)
bottle of 7.0 mL predilute (386R-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG
control
rhabdomyosarcoma
shipped in
wet ice
storage temp.
2-8°C
visualization
nuclear
Gene Information
human ... MYOD1(4654)
Analysis Note
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
General description
MyoD1, one of the MyoD family of myogenic helix-loop-helix transcription factors, combinedwith myogenin, plays a role in coordinating the differentiation of skeletal muscle. MyoD1 isexpressed in myoblasts before differentiation. Anti-MyoD1 immunostaining identifies cellscommitted to myogenesis in their earliest phase. In conjunction with other markers, antiMyoD1 may be used for the identification of rhabdomyosarcoma.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
MyoD1 Positive Control Slides, Product No. 386S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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N J Sebire et al.
Journal of clinical pathology, 56(6), 412-416 (2003-06-05)
The diagnosis of paediatric solid tumours is often based on small tissue needle biopsies in which many different entities demonstrate a "small round cell tumour" phenotype and in which there may be insufficient tissue to allow the interpretation of diagnostic
Raffaella A Morotti et al.
The American journal of surgical pathology, 30(8), 962-968 (2006-07-25)
Immunohistochemistry remains the current ancillary method of choice in the pathologic evaluation of small blue round-cell tumors. In at least 20% of cases of rhabdomyosarcoma (RMS), it is considered an essential factor in the final and/or differential diagnosis of the
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