推荐产品
生物来源
mouse
质量水平
100
500
偶联物
unconjugated
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
MRQ-58, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (382M-14)
vial of 0.5 mL concentrate (382M-15)
bottle of 1.0 mL predilute (382M-17)
vial of 1.0 mL concentrate (382M-16)
bottle of 7.0 mL predilute (382M-18)
制造商/商品名称
Cell Marque®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型
IgG1
控制
mantle cell lymphoma
运输
wet ice
储存温度
2-8°C
可视化
nuclear
基因信息
human ... SOX11(6664)
一般描述
SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination. citation Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).
质量
 IVD |  IVD |  IVD |  RUO |
联系
SOX-11 Positive Control Slides, Product No. 382S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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法规信息
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历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Bernd Weigle et al.
Oncology reports, 13(1), 139-144 (2004-12-08)
Malignant glioma comprises the majority of primary human brain tumors with 16,800 new cases reported each year in the USA. Its prognosis remains dismal despite numerous attempts to improve conventional therapeutic modalities. Therefore, much effort is devoted to the exploration
Tiemo Katzenberger et al.
British journal of haematology, 142(4), 538-550 (2008-06-20)
Mantle cell lymphoma (MCL) is an aggressive lymphoid tumour characterized by the translocation t(11;14)(q13;q32) and a poor clinical outcome (median survival: 3-4 years). Recent studies revealed that increased proliferation of the tumour cells and certain chromosomal aberrations, such as deletions
Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives.
Itziar Salaverria et al.
Haematologica, 91(1), 11-16 (2006-01-26)
Roshni Narurkar et al.
Biomarker research, 4, 6-6 (2016-03-08)
Cyclin D1 (CCND1) protein overexpression and/or the t(11;14)(q13;q32) translocation are the pathognomonic hallmarks of mantle cell lymphoma (MCL). However, there have been cases that lacked both t(11;14) and cyclin D1 protein but still had a gene expression profile suggesting a
Weifen Zeng et al.
The American journal of surgical pathology, 36(2), 214-219 (2012-01-19)
SOX11 expression has been recently shown to be useful in the diagnosis of mantle cell lymphoma (MCL), including cyclin D1-negative MCL with typical morphology. We evaluated SOX11 expression pattern in B-cell non-Hodgkin lymphoma (B-NHL) subtypes to confirm specificity and used
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