推荐产品
生物来源
mouse
质量水平
100
500
偶联物
unconjugated
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
MRQ-58, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形式
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (382M-14)
vial of 0.5 mL concentrate (382M-15)
bottle of 1.0 mL predilute (382M-17)
vial of 1.0 mL concentrate (382M-16)
bottle of 7.0 mL predilute (382M-18)
制造商/商品名称
Cell Marque™
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型
IgG1
控制
mantle cell lymphoma
运输
wet ice
储存温度
2-8°C
可视化
nuclear
基因信息
human ... SOX11(6664)
一般描述
SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination. citation Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).
质量
 IVD |  IVD |  IVD |  RUO |
联系
SOX-11 Positive Control Slides, Product No. 382S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
法规信息
监管及禁止进口产品
Tiemo Katzenberger et al.
British journal of haematology, 142(4), 538-550 (2008-06-20)
Mantle cell lymphoma (MCL) is an aggressive lymphoid tumour characterized by the translocation t(11;14)(q13;q32) and a poor clinical outcome (median survival: 3-4 years). Recent studies revealed that increased proliferation of the tumour cells and certain chromosomal aberrations, such as deletions
Bernd Weigle et al.
Oncology reports, 13(1), 139-144 (2004-12-08)
Malignant glioma comprises the majority of primary human brain tumors with 16,800 new cases reported each year in the USA. Its prognosis remains dismal despite numerous attempts to improve conventional therapeutic modalities. Therefore, much effort is devoted to the exploration
Mantle cell lymphoma: from pathology and molecular pathogenesis to new therapeutic perspectives.
Itziar Salaverria et al.
Haematologica, 91(1), 11-16 (2006-01-26)
M Hargrave et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 210(2), 79-86 (1997-10-23)
Sry, the mammalian Y-linked testis determining gene, is a member of a family of genes known as Sox genes, which encode transcription factors related by a DNA-binding motif termed the HMG box. Sox genes are known to have diverse roles
Kai Fu et al.
Blood, 106(13), 4315-4321 (2005-08-27)
Cyclin D1 overexpression is believed to be essential in the pathogenesis of mantle cell lymphoma (MCL). Hence, the existence of cyclin D1-negative MCL has been controversial and difficult to substantiate. Our previous gene expression profiling study identified several cases that
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