跳转至内容

尊敬的客户：

目前国际形势复杂多变，关税政策尚不明朗，这可能对我们的产品价格产生一定影响。在此情况下，我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性，如果您选择在此期间下单，我们将保留根据实际情况调整价格的权利。同时，我们也理解市场变化可能给您带来的困扰，因此如果在订单实际发货前因关税政策变动导致价格出现较大波动，默克将与您进行协商讨论并视情况对订单进行调整或取消。

Merck
CN
所有图片(1)

主要文件

安全信息

371R-1

Sigma-Aldrich

SOX-2 (SP76) Rabbit Monoclonal Antibody

登录查看公司和协议定价
所有图片(1)

About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

SP76, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (371R-14)
vial of 0.5 mL concentrate (371R-15)
bottle of 1.0 mL predilute (371R-17)
vial of 1.0 mL concentrate (371R-16)
bottle of 7.0 mL predilute (371R-18)

相关类别

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
Z742494Z742496Z679984
MyBlock™ HL Mini dry bath with heated lid AC/DC input 100 V / 240 V AC, EuroPlug

Z742495

MyBlock™ HL Mini dry bath with heated lid

MyBlock™ HL Mini dry bath with heated lid AC/DC input 100 V / 240 V AC, US 3-pin plug

Z742494

MyBlock™ HL Mini dry bath with heated lid

MyBlock™ HL Mini dry bath with heated lid AC/DC input 100 V / 240 V AC, UK plug

Z742496

MyBlock™ HL Mini dry bath with heated lid

MyBlock™ mini dry bath AC/DC input 100 / 240 V AC, US 2-pin plug

Z679984

MyBlock™ mini dry bath

feature

accuracy± 0.3 °C, temperature uniformity± 0.2 °C, incremental 0.1 °C

feature

accuracy± 0.3 °C, incremental 0.1 °C, temperature uniformity± 0.2 °C

feature

accuracy± 0.3 °C, incremental 0.1 °C, temperature uniformity± 0.2 °C

feature

-

capacity

, holds 1 block

capacity

, holds 1 block

capacity

, holds 1 block

capacity

, holds 1 block

parameter

+5 °C temp. range (100 °C)

parameter

+5 °C temp. range (100 °C)

parameter

+5 °C temp. range (100 °C)

parameter

5-100 °C temp. range

W × D × H

4 in. (10.5 cm) × 6 in. (15 cm) × 4.5 in. (11.5 cm)

W × D × H

4 in. (10.5 cm) × 6 in. (15 cm) × 4.5 in. (11.5 cm)

W × D × H

4 in. (10.5 cm) × 6 in. (15 cm) × 4.5 in. (11.5 cm)

W × D × H

-

manufacturer/tradename

Benchmark Scientific BSH200-HL-E

manufacturer/tradename

Benchmark Scientific BSH200-HL

manufacturer/tradename

Benchmark Scientific BSH200-HL-E-UK

manufacturer/tradename

Benchmark Scientific BSH200

packaging

pkg of 1

packaging

pkg of 1

packaging

pkg of 1

packaging

-

一般描述

It has been reported that anti-SOX-2 antibody recognizes lung squamous cell carcinoma (LSCC). A recent study[1] has demonstrated that extensive anti-SOX-2 staining was seen in over 90% of LSCC and largely paralleled p63 expression. Extensive anti-SOX-2 staining was seen in 21% of lung adenocarcinomas (LACA), including cases that were anti-p63-negative or only anti-p63 focally-positive. However, another recent study showed only 4.5% of LACA is positive for anti-SOX-2 expression.[2] In a study by Sholl et al, 29% of LACA cases exhibited at least focal p63 expression.[1] Combined p63 and SOX-2 expression was seen in 94% of LSCC and 12% of LACA with a statistically significant difference (P<0.0001) versus p63 alone. This study also showed that anti-CK5/6 had a good sensitivity but poor specificity for LSCC. Combined anti-CK5/6 and anti-p63 positivity was seen in 93% of LSCC and 24% of LACA. Anti-CK5/6+/anti-p63+/anti- SOX-2+ was detected in 93% of LSCC and only 9% of LACA. These results indicate that the sensitivity of anti-p63 is equally high but its specificity is similarly variable; it was seen at least focally in close to 30% of LACA. When used together, anti-p63+/anti-SOX-2+ applied to the same tumor cell population is >90% specific for LSCC. Anti-SOX-2 produced moderate-to-intense staining in all 50 cases of embryonal carcinoma components. The only other component that showed reactivity was the primitive neuroectodermal component in 11 of 14 (79%) of immature teratomas. In each of these positive staining foci, the staining varied from moderate-to-strong. Yolk sac tumor, seminoma, mature teratoma, choriocarcinoma, and IGCNU were uniformly negative, as were all the non-neoplastic parenchymal and stromal structures.[3]

质量


IVD
IVD
IVD
RUO

联系

SOX-2 Positive Control Slides, Product No. 371S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品？  

试试我们的产品选型工具.

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000431790
0000431790
0000407802
0000407802
0000402069

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Koji Tsuta et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 6(7), 1190-1199 (2011-05-31)
Recent clinical trials revealed that accurate histologic typing of non-small cell lung cancer, especially squamous cell carcinoma (SCC), is essential. We analyzed 10 antibodies expression in 150 SCC cases (53 well-, 51 moderately, and 46 poorly differentiated cases) and 159
Anuradha Gopalan et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(8), 1066-1074 (2009-04-28)
Stem cell markers, OCT3/4, and more recently SOX2 and growth differentiation factor 3 (GDF3), have been reported to be expressed variably in germ cell tumors. We investigated the immunohistochemical expression of these markers in different testicular germ cell tumors, and
Lynette M Sholl et al.
Applied immunohistochemistry & molecular morphology : AIMM, 18(1), 55-61 (2009-08-08)
Sox2 is a transcription factor that regulates embryonic stem cell pluripotency and drives commitment of airway precursor cells to basal-type and neuroendocrine cells in the developing lung. In cancer, Sox2 has been associated with a "stemness" phenotype that predicts for

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持