所有图片(1)
About This Item
经验公式（希尔记法）:
C14H17N3O3
CAS号:
分子量:
275.30
Beilstein:
5574454
MDL编号:
UNSPSC代码:
12352125
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
检测方案
≥95% (HPCE)
溶解性
DMF: soluble
acetonitrile: soluble
chloroform: soluble
methanol: soluble
荧光
λex 450 nm; λem 468 nm in methanol
适用性
suitable for fluorescence
SMILES字符串
CCN(CC)c1ccc2C=C(C(=O)NN)C(=O)Oc2c1
InChI
1S/C14H17N3O3/c1-3-17(4-2)10-6-5-9-7-11(13(18)16-15)14(19)20-12(9)8-10/h5-8H,3-4,15H2,1-2H3,(H,16,18)
InChI key
LYBMHAINSFEHRL-UHFFFAOYSA-N
一般描述
7-(Diethylamino)coumarin-3-carbohydrazide is a coumarin-hydrazide reagent typically used as a fluorescent chemical probe for labeling of cellular carbonyls.
应用
7-(Diethylamino)coumarin-3-carbohydrazide is used for derivatization and detection of carboxylic acid and carbonylated molecules such as lipid peroxidation products (LPP) by electrospray ionization-mass spectrometry (ESI-MS) in positive ion mode. It may be used as a fluorescent label for the determination of lipid aldehydes in food products by normal phase liquid chromatography (NPLC) coupled to ESI-MS and fluorescent detector (FLD) and for the derivatization of monoterpene alcohols in urine prior to analysis by high performance liquid chromatography(HPLC) with FLD coupled to ESI-MS.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
Derivatizing agent for carboxylic acid detection
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Ivana Milic et al.
Analytical chemistry, 85(1), 156-162 (2012-11-29)
Reactive oxygen species (ROS) and other oxidative agents such as free radicals can oxidize polyunsaturated fatty acids (PUFA) as well as PUFA in lipids. The oxidation products can undergo consecutive reactions including oxidative cleavages to yield a chemically diverse group
Roland J W Meesters et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 875(2), 444-450 (2008-10-11)
A method was developed for the determination of the monoterpene alcohols verbenol, myrtenol, perillyl alcohol, alpha-terpineol, Delta(3)-carene-10-ol, thymol and p-alpha,alpha-trimethylbenzylalcohol in urine samples. After an enzymatic cleavage of their glucuronide- and sulfate conjugates the monoterpene alcohols were converted in the
Selective labeling for the identification and semi-quantification of lipid aldehydes in food products
Hollebrands B, et al.
Analytical and Bioanalytical Chemistry, 85(1), 1-9 (2018)
M.L. Grayeski et al.
Analytical Chemistry, 59, 1203-1203 (1987)
Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by electrospray ionization-tandem mass spectrometry
Milic I, et al.
Analytical Chemistry, 85(1), 156-162 (2012)
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