跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

361593

Sigma-Aldrich

青蒿素

98%

别名:

青蒿素

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C15H22O5
CAS号:
63968-64-9
分子量:
282.33
MDL编号:
MFCD00081057
UNSPSC代码:
12352205
PubChem化学物质编号:
57649481
NACRES:
NA.79

质量水平

100

方案

98%

表单

solid

旋光性

[α]20/D +76°, c = 0.5 in methanol

mp

156-157 °C (lit.)

抗生素抗菌谱

parasites
viruses

应用

metabolomics
vitamins, nutraceuticals, and natural products

作用机制

enzyme | inhibits

SMILES字符串

C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4

InChI

1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

InChI key

BLUAFEHZUWYNDE-NNWCWBAJSA-N

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

青蒿素是从青蒿（Artemisia annua）中提取得到的。它具有抗癌、 抗原虫和抗病毒活性。青蒿素与脑干脑病有关。

应用

青蒿素已可用于：
  • 药物敏感性测定
  • 作为对毛状根所含青蒿素进行定量的标准品
  • 通过3-(4,5-二甲基-2-噻唑)-2,5-二苯基溴化四氮唑（MTT）测定来检测细胞活力
  • 作为抗疟药，用于研究自噬相关（ATG）基因在恶性疟原虫（ P. falciparum ）无性和有性血液期的作用

生化/生理作用

青蒿素是一种倍半萜内酯，是一种高效的抗疟疾（恶性疟疾）药物。青蒿素也是一种能有效对抗血吸虫病的驱虫剂（寄生虫）。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
0000383864
0000383864
MKCW0906
MKCS1414
MKCP2657

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. In what solvents is Product 361593, Artemisinin, soluble?

    According to the chemicals encyclopedia published by the Royal Society of Chemistry, artemisinin is expected to be soluble in most aprotic solvents and slightly soluble in oil. Sigma-Aldrich tests the solubility of this product in chloroform at 25 mg/mL. Our quality control is also able to prepare a 0.5% solution in methanol in order to measure the optical rotation.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Stimulation of artemisinin synthesis by combined cerebroside and nitric oxide elicitation in Artemisia annua hairy roots
Wang JW, et al.
Applied Microbiology and Biotechnology, 85(2), 285-292 (2009)
Pierre-Eric Campos et al.
Marine drugs, 17(3) (2019-03-17)
Chemical study of the CH₂Cl₂-MeOH (1:1) extract of the sponge Fascaplysinopsis reticulata collected in Mayotte highlighted three new tryptophan derived alkaloids, 6,6'-bis-(debromo)-gelliusine F (1), 6-bromo-8,1'-dihydro-isoplysin A (2) and 5,6-dibromo-8,1'-dihydro-isoplysin A (3), along with the synthetically known 8-oxo-tryptamine (4) and the
Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections
Pillai DR, et al.
Malaria Journal, 11(1), 131-131 (2012)
Deciphering genetic regulation of CD14 by SP1 through characterization of peripheral blood mononuclear transcriptome of P. faiciparum and P. vivax infected malaria patients
Chakraborty B, et al.
EBioMedicine, 37, 442-452 (2018)
Rita Piedade et al.
Expert opinion on drug metabolism & toxicology, 7(10), 1185-1200 (2011-09-09)
Plasmodium falciparum malaria is one of the world's most lethal infectious diseases, commanding millions of drug administrations per year. The pharmacogenetics of these drugs is poorly known, although its application can be pivotal for the optimized management of this disease.
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门