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Merck
CN
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主要文件

安全信息

356R-1

Sigma-Aldrich

Cytokeratin 5 & 6 (EP24 & EP67) Rabbit Monoclonal Primary Antibody

别名:

CK 5/6, cytokeratin 5/6

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP24 & EP67, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (356R-14)
vial of 0.1 mL concentrate Research Use Only (356R-14-RUO)
vial of 0.5 mL concentrate (356R-15)
vial of 1.0 mL concentrate (356R-16)
vial of 1.0 mL concentrate Research Use Only (356R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (356R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (356R-17)
vial of 7.0 mL pre-dilute ready-to-use (356R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (356R-18-RUO)

制造商/商品名称

Cell Marque™

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

控制

mesothelioma, prostate, squamous cell carcinoma ((lung))

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

基因信息

human ... KRT5(3852)

相关类别

一般描述

Twenty identified cytokeratins make up a complex family of intermediate filaments.1 Cytokeratin 5 (58kDa) & cytokeratin 6 (56kDa) are type II high molecular weight keratins that are expressed in a broad range of normal tissues including breast, prostate, mesothelium, skin and esophagus.1-3 Anti-Cytokeratin 5 & 6 is a useful immunohistochemical marker in the identification of mesothelioma and lung squamous cell carcinoma.1

质量

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

联系

Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris buffer, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide

制备说明

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Note: This IFU may not apply to your specific product lot.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number
0000408544
0000408544
0000394854
0000386882
0000373301

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R Lersch et al.
Molecular and cellular biology, 9(9), 3685-3697 (1989-09-01)
The mitotically active basal layers of most stratified squamous epithelia express 10 to 30% of their total protein as keratin. The two keratins specifically expressed in these cells are the type II keratin K5 (58 kilodaltons) and its corresponding partner
K Takahashi et al.
The Journal of biological chemistry, 270(31), 18581-18592 (1995-08-04)
The human type II keratin 6 (K6; 56 kDa) is expressed in a heterogeneous array of epithelial tissues under normal conditions, but is better known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or
Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas.
Ordo?ez, N.G.
Modern Pathology, 15, 6-10 (2002)
N G Ordóñez
The American journal of surgical pathology, 22(10), 1215-1221 (1998-10-20)
The immunohistochemical diagnosis of mesothelioma is commonly made by using a battery of antibodies that reacts with lung adenocarcinomas but not with epithelial mesotheliomas. Only recently have markers that are often expressed in mesotheliomas but not in adenocarcinomas been recognized.

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Antibodies as Raw Material

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