生物来源
rabbit
质量水平
100
500
偶联物
unconjugated
抗体形式
Ig fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形式
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (355A-14)
vial of 0.5 mL concentrate (355A-15)
bottle of 1.0 mL predilute (355A-17)
vial of 1.0 mL concentrate (355A-16)
bottle of 7.0 mL predilute (355A-18)
制造商/商品名称
Cell Marque™
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
控制
colorectal carcinoma, mesothelioma
运输
wet ice
储存温度
2-8°C
可视化
membranous
基因信息
human ... SLC2A1(6513)
一般描述
Glucose transporter type I (GLUT1), a prototype member of GLUT superfamily, is a membrane-associated erythrocyte glucose transport protein. It is a major glucose transporter in the mammalian blood-brain barrier, and also mediates glucose transport in endothelial cells of the vasculature, adipose tissue, and cardiac muscle. GLUT1 is detectable in many human tissues including those of colon, lung, stomach, esophagus, and breast. GLUT1 is overexpressed in malignant cells and in a variety of tumors that include the breast, pancreas, cervix, endometrium, lung, mesothelium, colon, bladder, thyroid, bone, soft tissues, and oral cavity. Immunohistochemical detection of GLUT1 has been shown to discriminate between reactive mesothelium and malignant mesothelioma in more than one study.Anti-GLUT1 is also useful in distinguishing benign endometrial hyperplasia from atypical endometrial hyperplasia and adenocarcinoma.
质量
 IVD |  IVD |  IVD |  RUO |
联系
GLUT1 Positive Control Slides, Product No. 355S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Alaa Afify et al.
Acta cytologica, 49(6), 621-626 (2006-02-03)
To evaluate the extent to which adenocarcinomas in body cavity fluids express GLUT-1 in comparison to currently available markers for adenocarcinomas. Archival paraffin-embedded cell blocks of serous fluids from 25 cases of benign effusions containing reactive mesothelial cells and 39
Value of immunohistochemical markers in differentiating benign from malignant mesothelial lesions
Acurio A, et al.
United States and Canadian Academy of Pathology Annual Meeting, 2008 null
Yasufumi Kato et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(2), 215-220 (2006-12-29)
The separation of benign reactive mesothelium (RM) from malignant mesothelial proliferation can be a major challenge. A number of markers have been proposed, including epithelial membrane antigen, p53 protein, and P-glycoprotein. To date, however, no immunohistochemical marker that allows unequivocal
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