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安全信息

340M-1

Sigma-Aldrich

Thyroglobulin (2H11+6E1) Mouse Monoclonal Antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

diluted ascites fluid

抗体产品类型

primary antibodies

克隆

2H11+6E1, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (340M-14)
vial of 0.5 mL concentrate (340M-15)
bottle of 1.0 mL predilute (340M-17)
vial of 1.0 mL concentrate (340M-16)
bottle of 7.0 mL predilute (340M-18)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG1

控制

thyroid

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

一般描述

Thyroglobulin (Tg) is the precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Tg is a high molecular weight glycoprotein found in normal thyroid follicular cells. Thyroglobulin is useful for identifying thyroid origin of carcinoma of papillary and follicular types in the setting of carcinoma of unknown primary.

联系

Thyroglobulin Positive Control Slides, Product No. 340S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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A R Judkins et al.
Human pathology, 30(11), 1373-1376 (1999-11-26)
We have previously shown that necrotic tumors retain their immunoreactivity for a range of cytokeratin antibodies. Some thyroid tumors undergo extensive necrosis after fine-needle aspiration (FNA) procedures. We evaluated the sensitivity of antibodies on necrotic thyroid tumors by examining a
Clara S Heffess et al.
Cancer, 95(9), 1869-1878 (2002-10-31)
Clear cell tumors of the thyroid gland in general are uncommon. Metastatic renal cell carcinoma (RCC) to the thyroid gland is a rare occurrence but must be considered in the differential diagnosis of a thyroid gland clear cell neoplasm to
S P Hammar
Human pathology, 29(12), 1393-1402 (1998-12-29)
Adenocarcinomas account for up to 60% of all metastatic neoplasms of unknown primary origin. In general, adenocarcinomas are the most difficult metastatic tumor to accurately identify the primary site. Some metastatic adenocarcinomas have distinctive histological features that allow for their
P A Bejarano et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(3), 189-194 (2000-09-12)
Thyroid transcription factor-1 (TTF-1), a member of the NKx2 family of homeodomain transcription factors, is a mediator of thyroid-specific transcription of the thyroglobulin (TG) gene. The combined immunohistochemical profile of TTF-1, TG, cytokeratin 7 (CK7), and cytokeratin 20 (CK20) in
D Bellet et al.
The Journal of clinical endocrinology and metabolism, 56(3), 530-533 (1983-03-01)
Human thyroglobulin (Tg) was used as an antigen in the development of antibodies by the hybridoma technique. From four antibodies that bound more than 40% labeled Tg, two were characterized (182/E4 and 211/A5). They were both of the immunoglobulin G

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