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Merck
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安全信息

338R-2

Sigma-Aldrich

TdT (EP266) Rabbit Monoclonal Primary Antibody

别名:

Terminal Deoxynucleotidyl Transferase

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About This Item

UNSPSC代码:
12352203

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP266, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (338R-24)
vial of 0.1 mL concentrate Research Use Only (338R-24-RUO)
vial of 0.5 mL concentrate (338R-25)
vial of 1.0 mL concentrate (338R-26)
vial of 1.0 mL concentrate Research Use Only (338R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (338R-27-RUO)
vial of 1.0 mL pre-dilute ready-to-use (338R-27)
vial of 7.0 mL pre-dilute ready-to-use (338R-28)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (338R-28-RUO)

制造商/商品名称

Cell Marque™

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

同位素/亚型

IgG

控制

thymus

运输

wet ice

储存温度

2-8°C

可视化

nuclear

基因信息

human ... DNTT(1791)

相关类别

一般描述

TdT (terminal deoxynucleotidyl transferase) is a template-independent DNA polymerase that adds nucleotides randomly to single-stranded DNA. This randomization plays a role in acquired immunity by increasing antigen receptor diversity and aiding in the generation of immunoglobulins and T cell antigen receptors. TdT expression is characteristic of lymphoid progenitor cells in thymus and tonsils. Anti-TdT is a useful marker for lymphoblastic lymphomas and has been observed in some cases of acute myeloid leukemia.

质量


IVD
IVD
IVD
RUO

联系

TdT Positive Control Slides, Product No. 338S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections)

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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James A Strauchen et al.
International journal of surgical pathology, 11(1), 21-24 (2003-02-25)
To investigate the occurrence of lymphoid progenitor cells in human tonsils, we studied tonsils from children and adults by immunohistochemistry by using a panel of antibodies to antigens associated with lymphoid progenitor cells, including terminal deoxynucleotidyl transferase (TdT), CD10 (CALLA)
Edward A Motea et al.
Biochimica et biophysica acta, 1804(5), 1151-1166 (2009-07-15)
Nearly every DNA polymerase characterized to date exclusively catalyzes the incorporation of mononucleotides into a growing primer using a DNA or RNA template as a guide to direct each incorporation event. There is, however, one unique DNA polymerase designated terminal
J Suzumiya et al.
The Journal of pathology, 182(1), 86-91 (1997-05-01)
Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3'hydroxyl ends of oligo- or polydeoxynucleotide initiators without a template. TdT is known as a useful marker for the
D A Arber et al.
American journal of clinical pathology, 106(4), 462-468 (1996-10-01)
The immunohistochemical evaluation of acute leukemia specimens has been limited in the past due of the inability to detect many lineage-related antigens in paraffin sections. With the improvement in immunohistochemical methods as well as the introduction of new antibodies, these

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