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Merck
CN

32884

Giemsa Stain

Modified Solution

别名:

Giemsa 染液 溶液, 天青曙红亚甲蓝

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关于此项目

化学文摘社编号:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
MA.02
MDL number:
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产品名称

Giemsa 染料,改良溶液, according to Giemsa

Quality Level

SMILES string

[Cl-].CN(C)c1ccc2N=C3C=CC(=[NH2+])C=C3Sc2c1

InChI key

NALREUIWICQLPS-UHFFFAOYSA-N

InChI

1S/C14H13N3S.ClH/c1-17(2)10-4-6-12-14(8-10)18-13-7-9(15)3-5-11(13)16-12;/h3-8,15H,1-2H3;1H

form

liquid

quality

according to Giemsa

technique(s)

UV/Vis spectroscopy: suitable

color

dark blue

pH

6.9

density

1.036 g/cm3 at 20 °C

suitability

passes test for UV spectrum

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

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Application

改进的吉姆萨染色可用于通过差异染色鉴定人的每条染色体。

Biochem/physiol Actions

当 Giemsa 染液对血涂片进行染色时,白细胞的细胞核和细胞质将呈现特征性的蓝色或粉红色。使用经纯化的伊红和噻嗪染料可使批间差异最小化。

General description

改进的吉姆萨染色是指pH值从通常的6.8变为9.0时的吉姆萨染色。

Other Notes

Giemsa 染液,改良,0.4% w/v,缓冲甲醇溶液,pH 6.8。含稳定剂。

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S R Patil et al.
Science (New York, N.Y.), 173(3999), 821-822 (1971-08-27)
Differential staining of human chromosomes can be obtained when the pH of Giemsa stain is changed to 9.0 from the usual 6.8. Such staining permits identification of all homolog pairs and distinct regions within chromosome arms. In most instances, the
Yonglian Zeng et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125, 110029-110029 (2020-02-29)
Faciogenital Dysplasia 1 (FGD1) has been involved in a variety of biological processes, including cytoskeleton restructuring, cell morphology, cell cycle progression, and cell polarity. Abnormal expression of FGD1 was also identified in several types of cancers, indicating its critical role
Xiao Liu et al.
EBioMedicine, 46, 42-53 (2019-08-10)
Twist-related protein 1 (TWIST1) plays an essential role in the carcinogenesis and metastasis of NSCLC. Our aims were to identify the molecule at the downstream of TWIST1 and to evaluate its potential as a diagnostic and a prognostic marker in
Zhenya Guo et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 124, 109857-109857 (2020-01-24)
TRAF-interacting protein (TRAIP) is a RING-type E3 ubiquitin ligase which has been implicated in various cellular processes, including NF-κB activation, DNA damage response, mitosis, and tumorigenesis. It is considered as a tumor suppressor in basal cell carcinomas and breast cancer
Jinjun Ye et al.
Cancer cell international, 21(1), 87-87 (2021-02-05)
LINC00963 is high-expressed in various carcinomas, but its expression and function in colorectal cancer (CRC) have not been explored. This study explored the role and mechanism of LINC00963 in CRC. The expression of LINC00963 in CRC and its relationship with

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