biological source
rabbit
conjugate
unconjugated
antibody form
Ig fraction of antiserum
antibody product type
primary antibodies
clone
EP109, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (324R-14), vial of 0.5 mL concentrate (324R-15), vial of 1.0 mL concentrate (324R-16), vial of 1.0 mL pre-dilute ready-to-use (324R-17), vial of 7.0 mL pre-dilute ready-to-use (324R-18)
manufacturer/tradename
Cell Marque®
concentration
0.1-0.5 μg/mL (predilute), 10-500 μg/mL (concentrate)
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)
isotype
IgG
control
prostate carcinoma
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... KLK3(354)
General description
Prostate-Specific Antigen (PSA) is a 33 kDa protein primarily produced by the prostatic epithelium and the epithelial lining of the periurethral glands. PSA is strongly expressed in both normal and neoplastic prostatic tissue. Anti-PSA is most useful in determining the prostatic origin of carcinomas in non-prostate tissues (metastatic disease) using IHC techniques.,,,
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and format
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Note: This IFU may not apply to your specific product lot.
Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
Analysis Note
Canada - IVD
European Union - IVD
Japan - RUO
United States - IVD
European Union - IVD
Japan - RUO
United States - IVD
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Do not freeze
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Prostate specific antigen: a decade of discovery -- what we have learned and where we are going.
Polascik, T.J., et al.
The Journal of Urology, 162, 293-306 (1999)
Immunohistochemical labelling for prostate specific antigen in nonprostatic tissues.
Alanen, K.A., et al.
Pathology Research and Practice, 192, 233-237 (1996)
Diagnostic utility of immunohistochemistry in morphologically difficult prostate cancer: review of current literature.
Varma, M., and Jasani, B.
Histopathology, 47, 1-16 (2005)
T J Polascik et al.
The Journal of urology, 162(2), 293-306 (1999-07-20)
Many advances have occurred during the last decade in the clinical use of prostate specific antigen (PSA) for detecting, staging and monitoring prostate cancer. We review the clinical usefulness and limitations of serum PSA as a tumor marker of prostate
Prostate-specific antigen.
Stenman, U.H., et al.
Seminars in Cancer Biology, 9, 83-93 (1999)
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