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Merck
CN
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文件

安全信息

320M-1

Sigma-Aldrich

Cytokeratin 20 (Ks20.8) Mouse Monoclonal Antibody

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UNSPSC代码:
12352200
NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

Ks20.8, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (320M-14)
vial of 0.5 mL concentrate (320M-15)
bottle of 1.0 mL predilute (320M-17)
vial of 1.0 mL concentrate (320M-16)
bottle of 7.0 mL predilute (320M-18)

制造商/商品名称

Cell Marque™

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:500

同位素/亚型

IgG2aκ

控制

colon carcinoma

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

基因信息

human ... KRT20(54474)

相关类别

一般描述

Cytokeratin 20 is a 46-kDa intermediate filament protein that reacts primarily with gastricand intestinal epithelium, urothelium, and Merkel cells. Anti-Cytokeratin 20 is usefulin the identification of specific types of these epithelial cells under normal, hyperplastic,and neoplastic conditions. Cytokeratin 20 has been detected in various adenocarcinomas,including those of the colon and stomach. Merkel cell carcinomas have shown reactivity. Incontrast, carcinomas of the breast are generally non-reactive.

质量


IVD
IVD
IVD
RUO

联系

Cytokeratin 20 Positive Control Slides , Product No. 320S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

法规信息

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A Rullier et al.
The American journal of surgical pathology, 24(6), 870-876 (2000-06-08)
In the liver, the immunostaining of cytokeratins (CK) 7 and 20 has been used to distinguish usual peripheral cholangiocarcinomas (CC) and colorectal carcinoma metastasis (CRM). However, other subtypes of CC are not infrequent and may be particularly difficult to distinguish
T Tot
Cancer, 85(1), 171-177 (1999-01-28)
Metastatic adenocarcinoma in the liver with an unidentified primary tumor site is a common clinical problem. Pathologists often are asked to identify the primary tumor site. The histologic picture itself usually is not helpful, because the histology may be similar
Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas
Wang NP, Zee S, Zarbo RJ, Bacchi CE, Gown AM
Appl. Immunohistochem., 3, 99-107 (1995)
T Tot
Cancer, 92(10), 2727-2732 (2001-12-18)
Immunohistochemistry is a useful method in the differential diagnosis between pleural mesotheliomas and metastatic adenocarcinomas to the pleura. Cytokeratin (CK) 5-6 is one of the most specific mesothelioma-associated antibodies. Cytokeratin 20 and CK7 have been used successfully in studies determining
Sean K Lau et al.
Human pathology, 33(12), 1175-1181 (2003-01-07)
Distinguishing hepatocellular carcinoma (HCC) from cholangiocarcinoma (CC) and metastatic adenocarcinoma (MA) involving the liver can be problematic, often requiring the use of immunohistochemistry to facilitate diagnosis. Hep Par 1, a monoclonal antibody with expression confined primarily to benign and malignant
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