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生物来源
mouse
偶联物
unconjugated
抗体形式
diluted ascites fluid
抗体产品类型
primary antibodies
克隆
Ks 17.E3, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (317M-14)
vial of 0.5 mL concentrate (317M-15)
bottle of 1.0 mL predilute (317M-17)
vial of 1.0 mL concentrate (317M-16)
bottle of 7.0 mL predilute (317M-18)
制造商/商品名称
Cell Marque™
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型
IgG2b
控制
cervix neoplasia III
运输
wet ice
储存温度
2-8°C
可视化
cytoplasmic
基因信息
human ... KRT17(3872)
一般描述
Cytokeratin 17 is 46 kD intermediate filament found in simple epithelia sometimes in association with Cytokeratin 7. This antibody has been used to distinguish cervical immature squamous metaplasia from high grade cervical intraepithelial neoplasia (CIN III). Anti-CK 17 also labels myoepithelial cells in the benign breast tissue. CK 17 labelling of breast carcinoma cells (so-called basal phenotype) has been associated with a poor prognosis.
质量
 IVD |  IVD |  IVD |  RUO |
联系
Cytokeratin 17 Positive Control Slides , Product No. 317S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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法规信息
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分析证书(COA)
Lot/Batch Number
S Regauer et al.
Histopathology, 50(5), 629-635 (2007-03-31)
Atypical immature metaplasia (AIM) refers to a full-thickness intraepithelial basaloid lesion in the uterine cervix that features both metaplasia and atypia and is therefore difficult to distinguish from high-grade cervical intraepithelial neoplasia (CIN III). p16 is a marker for human
Jolise E Martens et al.
Anticancer research, 24(2B), 771-775 (2004-05-27)
Basic research on HPV has focused on identifying the genetic changes that lead to cervical carcinoma. However, while focusing on the molecular biology of the cancer, understanding of its cellular biology has lagged: the target cell of the HPV infection
Peiguo G Chu et al.
The American journal of surgical pathology, 29(3), 359-367 (2005-02-24)
Pancreatobiliary and ampulla of Vater adenocarcinomas frequently metastasize to regional lymph nodes, liver, or lung and are difficult to diagnose because they lack specific immunohistochemical markers. We studied the expression of cytokeratin 7 (CK7), cytokeratin 17 (CK17), cytokeratin 20 (CK20)
Raanan Cohen-Kerem et al.
The Annals of otology, rhinology, and laryngology, 113(10), 821-827 (2004-11-13)
To assess cytokeratin-17 (CK17) as an immunohistochemical marker for squamous cell carcinoma of the larynx, we stained 63 tissue samples from 63 consecutive patients who were believed or suspected to have squamous cell carcinoma of the larynx for CK17 and
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