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Merck
CN

317861

Sigma-Aldrich

异硫氰酸苯酯

99%, for protein sequencing

别名:

PITC

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About This Item

线性分子式:
C6H5NCS
CAS号:
分子量:
135.19
Beilstein:
471392
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21

类型

for protein sequencing

质量水平

方案

99%

表单

liquid

折射率

n20/D 1.6515 (lit.)

沸点

218 °C (lit.)
221 °C

mp

−21 °C (lit.)

溶解性

water: insoluble

密度

1.132 g/mL at 20 °C (lit.)

官能团

isothiocyanate

储存温度

2-8°C

SMILES字符串

S=C=Nc1ccccc1

InChI

1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H

InChI key

QKFJKGMPGYROCL-UHFFFAOYSA-N

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应用

自动序列分析时用于蛋白质 N-末端氨基酸的衍生化作用。二噻二氮杂富瓦烯的合成单体。
用于伯胺和仲胺的衍生化试剂。用于通过 Edman 降解法进行多肽测序以及通过 HPLC 进行氨基酸分析。

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

190.4 °F - closed cup

闪点(°C)

88 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

Journal of the Chemical Society. Chemical Communications, 601-601 (1993)
F Lai et al.
BioTechniques, 14(4), 642-649 (1993-04-01)
Pre-column derivatizations of amino acids often present two major challenges: 1) automation, due to the multi-step manipulations for pH control, reagent addition, mixing and extraction, and 2) effect of matrices in the sample such as salts, buffers and surfactants. Both
Amin Zolali et al.
Combinatorial chemistry & high throughput screening, 17(7), 610-613 (2014-03-19)
An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.
One-pot dehydrations using phenyl isothiocyanate.
Majetich G, et al.
Tetrahedron Letters, 56(23), 3326-3329 (2015)
Determination of phenylisothiocyanate derivatives of amphetamine and its analogues in biological fluids by HPLC-APCI-MS or DAD.
Bogusz MJ, et al.
Journal of Analytical Toxicology, 21(1), 59-69 (1997)

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