生物来源
(Leuconostoc spp)
质量水平
形式
powder
分子量
Mr ~6,000
颜色
white
mp
483 °C ((901 °F ))
溶解性
water: 1.5 g/10 mL, colorless to faintly yellow
储存温度
room temp
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
InChI key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
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一般描述
葡聚糖是 D-吡喃葡萄糖的一种细胞外细菌聚合物。它主要包括主链中的α-(1→6)个连接和可变数量的 α-(1→2)，α-(1→3)，α-(1→4)个支链连接。
葡聚糖是由线性α(1→6)连接的葡萄糖单元和α(1→3)连接启动的支链组成的支链葡聚糖。葡聚糖的分子量范围为10,000至150,000 Kd。葡聚糖在许多应用中被用作血容量扩张剂、稳定剂、基质组分、结合平台、润滑剂和物理结构组分。由于低分子量的葡聚糖具有不同的粘度、聚集性和渗透性能，因此通常比高分子量的葡聚糖更受欢迎。
应用
来自明串珠菌属的葡聚糖已用于：
- 酪蛋白酸的糖基化研究与葡萄糖相比碳水化合物链长度增加的影响
- 用于基质辅助激光解吸电离飞行时间质谱（MALDI-TOF）的质量校准，用于银纳米颗粒（AgNP）的表征
- 作为一种无毒稳定剂，用于评估三氧化钨（WO3）纳米颗粒的体内给药
生化/生理作用
葡聚糖被用作一种药物，特别是作为一种血浆体积膨胀剂。它在食品、制药和化学工业中也可用作佐剂、乳化剂、载体和稳定剂。Sephadex 是一种交联葡聚糖，通常用于蛋白质的分离和纯化。在食品工业中，右旋糖酐可作为果酱和冰淇淋的增稠剂。它阻碍了糖结晶，并增强了水分保持。这样可以保留几种食物的味道和外观。
WGK
WGK 2
个人防护装备
Eyeshields, Gloves, type N95 (US)
Thomas Rath et al.
Nephron. Clinical practice, 114(1), c81-c88 (2009-11-06)
Intravenous iron supplementation is a basic principle in the therapy of haemodialysis (HD) patients with renal anaemia. In the Iron Dextran in Renal Anaemia (IDIRA) study, we analysed the efficacy of a therapy with low-molecular-weight iron dextran (LMW-ID) in stable
Eugen Sisu et al.
Rapid communications in mass spectrometry : RCM, 20(2), 209-218 (2005-12-15)
A combined methodology for obtaining at the preparative scale and characterization by nanoelectrospray ionization (nanoESI) quadrupole time-of-flight (QTOF) mass spectrometry (MS) and tandem MS (MS/MS) of linear polysaccharides modified at the reducing end is presented. Two polydisperse maltodextrins (1000 and
R J Stenekes et al.
Biomaterials, 22(13), 1891-1898 (2001-06-09)
In this paper, a novel method is presented for the preparation of dextran hydrogels and microspheres, based on crystallization. Although dextrans are known to be well soluble in water, precipitation was observed in concentrated aqueous solutions of low molecular weight
Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone).
Van Eerdenbrugh B, Taylor LS.
Pharmaceut. Res., doi: 10-doi: 10 (2012)
Melda Altikatoglu et al.
Artificial cells, blood substitutes, and immobilization biotechnology, 40(4), 261-265 (2012-01-28)
In the present study, the stabilizing effect of dextrans as additives on the denaturation and inactivation of glucose oxidase (GOD) was investigated. Three different molecular weighted dextrans (M(w) 17.5, 75, 188 kD) were used with different concentrations. Dramatically increased enzyme
相关内容
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.
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