推荐产品
生物来源
bovine bile
synthetic
质量水平
描述
anionic
检测方案
≥99.0% (T)
形式
powder
旋光性
[α]20/D +26±1°, c = 1% in ethanol
mp
238-240 °C
溶解性
ethanol: 10 mg/mL, clear (hot)
官能团
carboxylic acid
SMILES字符串
[H][C@@]12CC(=O)CC[C@]1(C)[C@@]3([H])CC(=O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])C(=O)C2)[C@H](C)CCC(O)=O
InChI
1S/C24H34O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-14,16-18,22H,4-12H2,1-3H3,(H,28,29)/t13-,14+,16-,17+,18+,22+,23+,24-/m1/s1
InChI key
OHXPGWPVLFPUSM-KLRNGDHRSA-N
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应用
脱氢胆酸可用于研究胆汁盐与铜离子在非缓冲系统中的相互作用。
生化/生理作用
脱氢胆酸是胆酸的铬酸氧化产物，其在生理条件下不存在。当用于动物实验时，它会刺激胆汁分泌。
制备说明
脱氢胆酸在10mg/ml的热乙醇中可产生澄清溶液。
其他说明
用于通过生物转化生产鹅去氧胆酸
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
H. Sawada et al.
Adv. Biotechnol., [Proc. Int. Ferment. Symp.], 6th (1980) (C.Vezina,K.Singh eds., 3, 495-495 (1981)
R D Soloway et al.
The Journal of clinical investigation, 52(3), 715-724 (1973-03-01)
[24-(14)C]Dehydrocholic acid (triketo-5-beta-cholanoic acid) was synthesized from [24-(14)C]cholic acid, mixed with 200 mg of carrier, and administered intravenously to two patients with indwelling T tubes designed to permit bile sampling without interruption of the enterohepatic circulation. More than 80% of
G Feroci et al.
Journal of pharmaceutical sciences, 84(1), 119-125 (1995-01-01)
Interaction of bile salts with Cu2+ ions in unbuffered systems containing 0.15 M NaNO3 was followed by measuring polarographic limiting currents and half-wave potentials. Whereas taurocholate forms neither soluble complexes nor compounds of limited solubility, cholate, glycocholate, and dehydrocholate from
Xue Qiao et al.
Journal of chromatography. A, 1218(1), 107-117 (2010-11-30)
Animal biles and gallstones are popularly used in traditional Chinese medicines, and bile acids are their major bioactive constituents. Some of these medicines, like cow-bezoar, are very expensive, and may be adulterated or even replaced by less expensive but similar
Boqiao Sun et al.
Biotechnology and bioengineering, 110(1), 68-77 (2012-07-19)
Ursodeoxycholic acid (UDCA) is a bile acid of industrial interest as it is used as an agent for the treatment of primary sclerosing cholangitis and the medicamentous, non-surgical dissolution of gallstones. Currently, it is prepared industrially from cholic acid following
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