主要文件

查看所有文档

30432

丹酰尸胺

Name: 丹酰尸胺
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

别名:

N-（5-氨基戊基）-5-二甲基氨基萘-1-磺酰胺, N-（二甲基氨基萘磺酰）-1，5-戊二胺, 丹酰尸胺

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₇H₂₅N₃O₂S

化学文摘社编号:

10121-91-2

分子量:

335.46

UNSPSC Code:

12352108

NACRES:

NA.32

PubChem Substance ID:

57648439

EC Number:

233-326-9

Beilstein/REAXYS Number:

2951070

MDL number:

MFCD00042704

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

product line

BioReagent

Quality Level

100

assay

≥99.0% (HPLC)

mp

137-140 °C

fluorescence

λ_ex 335 nm; λ_em 518 nm in methanol, λ_ex 338 nm; λ_em 500 nm (Reaction product)

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN

InChI

1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3

InChI key

MLEBFEHOJICQQS-UHFFFAOYSA-N

说明

Application

丹酰戊二胺（MDC），一种自荧光染料，被用来监测细胞自我吞噬。因为离子捕获和特异性膜脂互作，MDC在自噬泡中累积。

Biochem/physiol Actions

纤维蛋白稳定因子抑制剂；表皮生长因子（EGF）内化抑制剂酰胺顺反异构转化酶分析荧光底物。

自发荧光染料丹酰尸胺或单丹磺酰尸胺（MDC）通常用于监测自噬。由于离子捕获和与膜脂质的特异性相互作用的组合，单丹磺酰尸胺优先在自噬泡中积累。

Packaging

无底玻璃瓶。内容物在插入式融锥内。

空气敏感，在惰性气体下处理

Other Notes

在甲醇（10 mg/mL）中测试丹酰尸胺的溶解度。据报道，丹酰尸胺可溶于 DMSO 和乙酸。

Still not finding the right product?

Explore all of our products under 丹酰尸胺

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Targeting androgen receptor leads to suppression of prostate cancer via induction of autophagy.

Qi Jiang et al.

The Journal of urology, 188(4), 1361-1368 (2012-08-22)

Androgen receptor has a critical role in prostate cancer development and progression. Cell death via autophagy may also contribute to prostate cancer progression. We determined the role and regulatory effects of androgen receptor on the autophagy process of prostate cancer

Transamidating enzymes. I. Rapid chromatographic assays.

L Lorand et al.

Analytical biochemistry, 44(1), 207-220 (1971-11-01)

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

H T Haigler et al.

The Journal of biological chemistry, 255(4), 1239-1241 (1980-02-25)

The binding and internalization of 125I-epidermal growth factor (125I-EGF) was studied in cultures of BALB 3T3 cells using a novel method that involved removal of cell-surface hormone by treatment with acetic acid under conditions that did not remove internalized hormone.

查看所有相关文献

全球贸易项目编号

货号	GTIN
30432-100MG	04061826666838
30432-1G	04061826666845