推荐产品
生物来源
mouse
质量水平
100
500
偶联物
unconjugated
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
AE3, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (303M-14)
vial of 0.5 mL concentrate (303M-15)
bottle of 1.0 mL predilute (303M-17)
vial of 1.0 mL concentrate (303M-16)
bottle of 7.0 mL predilute (303M-18)
制造商/商品名称
Cell Marque™
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同位素/亚型
IgG1κ
控制
prostate
运输
wet ice
储存温度
2-8°C
可视化
cytoplasmic
基因信息
human ... KRT1(3848)
一般描述
Anti-cytokeratin, high molecular weight (AE3) is capable of recognizing all basic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. Members of the acidic and basic subfamilies are found together in pairs. Since each epithelium contains at least one acidic and one basic keratin, this antibody is used to observe the distribution of keratin-containing cells in normal epithelia and to identify neoplasms derived from such epithelium.
质量
 IVD |  IVD |  IVD |  RUO |
联系
Cytokeratin, HMW Positive Control Slides, Product No. 303S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
W G Nelson et al.
Cancer research, 44(4), 1600-1603 (1984-04-01)
The expression of specific keratin polypeptides in human neoplasms was investigated by the immunoblot technique using monoclonal anti-keratin antibodies. Mr 50,000 and 58,000 keratins, recognized by AE1 and AE3 antibodies, respectively, were detected only in carcinomas of stratified epithelial origin
Monoclonal antibody studies of mammalian epithelial keratins: a review.
T T Sun et al.
Annals of the New York Academy of Sciences, 455, 307-329 (1985-01-01)
V Eusebi et al.
The American journal of surgical pathology, 14(8), 737-747 (1990-08-01)
We present four cases of a malignant thyroid tumor showing morphologic, immunocytochemical, and ultrastructural features of endothelial cell differentiation. The tumor cells had epithelioid features and displayed strong immunoreactivity for keratin. There was no evidence of follicular or C-cell differentiation
A Lopez-Beltrán et al.
Virchows Archiv : an international journal of pathology, 438(6), 552-557 (2001-07-27)
Lymphoepithelioma-like carcinoma (LELCA) of the urinary bladder is a rare variant of bladder cancer characterized by a malignant epithelial component densely infiltrated by lymphoid cells. It is characterized by indistinct cytoplasmic borders and a syncytial growth pattern. These neoplasms deserve
R A Weiss et al.
The Journal of cell biology, 98(4), 1397-1406 (1984-04-01)
The polypeptide composition of epidermal keratin varies in disease. To better understand the biological meaning of these variations, we have analyzed keratins from a number of human epidermal diseases by the immunoblot technique using AE1 and AE3 monoclonal antikeratin antibodies.
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