所有图片(1)
About This Item
线性分子式:
HO3SCH2CH(NH2)CO2H·H2O
CAS号:
分子量:
187.17
Beilstein:
3714036
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
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产品名称
L-磺基丙氨酸 一水合物, ≥99.0% (T)
质量水平
方案
≥99.0% (T)
表单
powder or crystals
旋光性
[α]20/D +7.5±0.5°, c = 5% in H2O
技术
LC/MS: suitable
颜色
white to faint yellow
mp
267 °C (dec.) (lit.)
溶解性
H2O: soluble
应用
peptide synthesis
SMILES字符串
[H]O[H].N[C@@H](CS(O)(=O)=O)C(O)=O
InChI
1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1
InChI key
PCPIXZZGBZWHJO-DKWTVANSSA-N
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相关类别
应用
氨基酸分析的内标。
生化/生理作用
L-半胱磺酸是一种 L-半胱氨酸的氧化产物。L-半胱磺酸是半胱氨酸亚磺酸的类似物，可用于研究脑中的兴奋性氨基酸，例如与半胱氨酸亚磺酸受体结合的氨基酸。L-半胱磺酸是几种大鼠代谢型谷氨酸受体（mGluRs）的有用的激动剂。
L-半胱磺酸是含硫的天冬氨酸类似物，其可以用作细菌天冬氨酸：丙氨酸反向转运体（AspT）交换天冬氨酸和其他天冬氨酸生物系统的竞争性抑制剂。L-半胱磺酸用于单体表面活性剂的开发。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
B Meldrum
Epilepsia, 25 Suppl 2, S140-S149 (1984-01-01)
Amino acids provide the most universal and important inhibitory (gamma-aminobutyric acid (GABA), glycine) and excitatory (glutamate, aspartate, cysteic acid, cysteine sulphinic acid) neurotransmitters in the brain. An anticonvulsant action may be produced (1) by enhancing inhibitory (GABAergic) processes, and (2)
Qi Shi et al.
The Journal of pharmacology and experimental therapeutics, 305(1), 131-142 (2003-03-22)
Moderate hyperhomocysteinemia is associated with several diseases, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, and spina bifida. However, the mechanisms for their pathogenesis are unknown but could involve the interaction of homocysteine or its metabolites with molecular targets such
A E Kingston et al.
Neuropharmacology, 37(3), 277-287 (1998-07-29)
Comparison of the pharmacological effects of a range of sulphur-containing amino acids on human mGluR1alpha and mGluR5a has been undertaken. cDNAs of each mGluR were transfected into a Syrian hamster tumour cell line AV12-664 that was previously transfected with the
Internal standards for amino acid analysis.
J F Riordan et al.
Methods in enzymology, 47, 31-40 (1977-01-01)
Naoko Arashida et al.
Analytica chimica acta, 954, 77-87 (2017-01-14)
Amino acids and their related metabolites play important roles in various physiological processes and have consequently become biomarkers for diseases. However, accurate quantification methods have only been established for major compounds, such as amino acids and a limited number of
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