质量水平
检测方案
≥95% (HPLC)
形式
powder
溶解性
ethanol: soluble (10mg/mL)
荧光
λex 529 nm; λem 600 nm in 0.1 M Tris pH 8.4
储存温度
2-8°C
SMILES字符串
CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C(C)=C3Oc2c1)OCCCCCCCCCCCC
InChI
1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-37-27-28-39-42(33-37)54-45-36(3)41(47)30-29-40(45)46-39/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3
InChI key
FYOMYGYHAZESGQ-UHFFFAOYSA-N
一般描述
脂肪酶底物 (1,2-二-O-月桂酰 -外消旋-甘油-3-(戊二酸 6-甲基试卤灵酯, DGGR)是脂肪酶的显色底物。它可用于比色法,用于测量脂肪酶活性。该底物在被脂肪酶消化时会产生一种红紫色化合物甲基试卤灵。
应用
脂肪酶底物可用作高通量筛选试验中的底物,用于测量利普司他汀形成而导致的脂肪酶活性。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
International journal of molecular sciences, 23(21) (2022-11-12)
Atopic dermatitis (AD), the most common inflammatory skin disorder, is a multifactorial disease characterized by a genetic predisposition, epidermal barrier disruption, a strong T helper (Th) type 2 immune reaction to environmental antigens and an altered cutaneous microbiome. Microbial dysbiosis
Current microbiology, 75(5), 580-587 (2017-12-20)
Pancreatic lipase inhibitors, such as tetrahydrolipstatin (orlistat), are used in anti-obesity treatments. Orlistat is the only anti-obesity drug approved by the European Medicines Agency (EMA). The drug is synthesized by saturation of lipstatin, a β-lactone compound, isolated from Streptomyces toxytricini
Journal of lipid research, 61(8), 1203-1220 (2020-06-04)
Angiopoietin-like protein (ANGPTL)8 has been implicated in metabolic syndrome and reported to regulate adipose FA uptake through unknown mechanisms. Here, we studied how complex formation of ANGPTL8 with ANGPTL3 or ANGPTL4 varies with feeding to regulate LPL. In human serum
Food microbiology, 82, 316-324 (2019-04-28)
Biofilm-forming Bacillus species are often involved in contamination of dairy products and therefore present a major microbiological challenge in the field of food quality and safety. In this study, we sequenced and analyzed the genomes of milk- and non-milk-derived Bacillus
Biochemical and biophysical research communications, 534, 498-503 (2020-11-27)
We previously demonstrated that angiopoietin-like 8 (ANGPTL8) forms a localized complex with ANGPTL4 to reduce its lipoprotein lipase (LPL)-inhibitory activity and enable increased postprandial uptake of fatty acids (FA) into adipose tissue. Because prolonged cold exposure may increase adipose tissue
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