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Merck
CN

30030

Sigma-Aldrich

罗布麻苷

≥96% (HPLC)

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别名:
K-Strophanthidin-D-cymaroside, K-Strophanthin-α
经验公式(希尔记法):
C30H44O9
CAS号:
分子量:
548.66
Beilstein:
101370
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥96% (HPLC)

SMILES字符串

CO[C@H]1C[C@@H](O[C@H](C)[C@H]1O)O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6

InChI

1S/C30H44O9/c1-17-26(33)23(36-3)13-25(38-17)39-19-4-9-28(16-31)21-5-8-27(2)20(18-12-24(32)37-15-18)7-11-30(27,35)22(21)6-10-29(28,34)14-19/h12,16-17,19-23,25-26,33-35H,4-11,13-15H2,1-3H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28+,29+,30+/m1/s1

InChI key

XQCGNURMLWFQJR-ZNDDOCHDSA-N

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相关类别

应用

Cymarin was used to study the effect of cardiac glycosides on vascular smooth muscles and ion transport.

生化/生理作用

Cymarin is a cardiac glycoside and is classified as cardiotonic steroid. It inhibits ion transport by decreasing the activity of (Na-K)-ATPase.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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The cholinergic link in the genesis of the cardiac arrhythmias induced by the intracerebroventricular administration of K-strophantin in anaesthetized rats.
A David et al.
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 23(2), 83-85 (1982-04-01)
Z B Skorzova et al.
Sudebno-meditsinskaia ekspertiza, 32(2), 35-36 (1989-04-01)
Private technique of extraction isolation and purification, chromatographic detection and photometric determination of zimarin in urine is suggested. Detection limit is 0.01 mg, determination limit is 0.1 mg of glycoside in 100 ml of urine. Method makes it possible to
[Validity of cardioactive glycosides].
A U Sinardi et al.
Minerva anestesiologica, 58(10), 639-645 (1992-10-01)
E V Lopatina et al.
Bulletin of experimental biology and medicine, 146(6), 744-746 (2009-06-11)
We studied the role of cardiac glycosides in the regulation of the growth of retinal tissue explants from 10-12-day-old chicken embryos in organotypic culture. The studied compounds produced a dose-dependent effect on cell proliferation in retinal tissue explants. Ouabain (10(-13)M)
C Giunta et al.
General pharmacology, 16(3), 183-188 (1985-01-01)
Ouabain and K-strophanthoside promote an enhancement of Na+/K+-ATPase activity in a range of cardioglycoside concentrations from 100 nM to 100 pM, with a maximum (+30%) between 10 and 4 nM. Binding experiments with [3H]ouabain show upward-curved Scatchard plots and evidence

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