生物来源
mouse
质量水平
100
500
偶联物
unconjugated
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
SMMS-1, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形式
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (298M-14)
vial of 0.5 mL concentrate (298M-15)
bottle of 1.0 mL predilute (298M-17)
vial of 1.0 mL concentrate (298M-16)
bottle of 7.0 mL predilute (298M-18)
制造商/商品名称
Cell Marque™
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同位素/亚型
IgG1κ
控制
breast
运输
wet ice
储存温度
2-8°C
可视化
cytoplasmic
基因信息
human ... MYH11(4629)
一般描述
Smooth Muscle Myosin, heavy chain (SMMS-1) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMMS-1 is also an amyoepithelium-associated protein. Anti-SMMS-1 is a mouse monoclonal antibody to smooth muscle myosin, a heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in identifying myoepithelial cells in benign sclerosing breast lesions and demonstrating their absence of invasive breast carcinomas.
质量
 IVD |  IVD |  IVD |  RUO |
联系
Myosin, Smooth Muscle Positive Control Slides, Product No. 298S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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法规信息
监管及禁止进口产品
Robert W Werling et al.
The American journal of surgical pathology, 27(1), 82-90 (2002-12-28)
Identification of myoepithelial cells using antibodies to cytoskeletal proteins, such as smooth muscle myosin heavy chain (SMM-HC) and calponin, can play an important role in distinguishing invasive carcinoma from its histologic mimics. However, antibodies to these proteins may also cross-react
D Lazard et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(3), 999-1003 (1993-02-01)
The expression of several differentiation markers in normal human mammary gland myoepithelium and in certain stromal fibroblasts ("myofibroblasts") associated with breast carcinomas was studied by immunofluorescence microscopy of frozen sections. Several antibodies to smooth muscle-specific proteins (smooth muscle alpha-actin, smooth
Nikolay K Popnikolov et al.
American journal of clinical pathology, 120(2), 161-167 (2003-08-23)
We immunohistochemically compared benign myoepithelial tumors (adenomyoepitheliomas [AMEs]) and metaplastic matrix-producing (MMP-CA) and spindle cell (MSC-CA) carcinomas of the breast to identify helpful diagnostic markers. Normal myoepithelial cells (MECs) consistently expressed cytokeratin, alpha-smooth muscle actin (SMA), myosin, S-100, CD10, and
S N Agoff et al.
Applied immunohistochemistry & molecular morphology : AIMM, 9(2), 164-169 (2001-06-09)
Distinguishing low grade endometrial stromal sarcoma (ESS) from benign smooth muscle proliferations like cellular leiomyoma (CL) can be problematic; because of differing treatments and prognosis, this distinction is important. The authors tested the hypothesis that low grade ESS could be
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