293M-9
MUC6 (MRQ-20) Mouse Monoclonal Antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MRQ-20, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
7
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
biological source
mouse
conjugate
unconjugated
antibody form
diluted ascites fluid
antibody product type
primary antibodies
clone
MRQ-20, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (293M-94)
vial of 0.5 mL concentrate (293M-95)
bottle of 1.0 mL predilute (293M-97)
vial of 1.0 mL concentrate (293M-96)
bottle of 7.0 mL predilute (293M-98)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1
control
stomach
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... MUC6(4588)
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
MUC6 is a secretory mucin that is part of a family of at least 14 high molecular-weightglycoproteins made by many epithelial tissues. MUC6 is preferentially expressed in nonneoplastic gastric tissue, specifically in the pyloric glands. During neoplastic transformation,mucin expression may be altered within these tissues leading to particular patterns ofexpression.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
MUC6 Positive Control Slides, Product No. 293S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Seog-Yun Park et al.
Archives of pathology & laboratory medicine, 131(10), 1561-1567 (2007-10-10)
Although identification of the primary tumor in patients with metastatic adenocarcinoma has a profound clinical impact, diagnosing the organ of origin is frequently difficult. Because none of the individual immunohistochemical markers used for tissue identification are both site specific and
Emad A Rakha et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(10), 1295-1304 (2005-06-25)
Mucins are a large family of glycoproteins expressed by many epithelial cells and their malignant counterparts. Much interest has been focused on expression of its members in breast cancer because of their potential role as prognostic indicators and their involvement
T Mizoshita et al.
Histology and histopathology, 22(3), 251-260 (2006-12-14)
We have previously demonstrated links between clinicopathological findings and phenotypes using several gastric and intestinal phenotypic markers in stomach and pancreatic cancers. However, the clinicopathological significance of the phenotype and Cdx2 expression has hitherto remained unclear in colorectal carcinogenesis. We
Emmanuelle Leteurtre et al.
World journal of gastroenterology, 12(21), 3324-3331 (2006-05-31)
To investigate the expression of the four secreted gel-forming mucins (MUC2, MUC5AC, MUC5B and MUC6) in a series of gastric carcinomas, classified according Lauren's, Mulligan's, WHO and Goseki's classifications, with special attention to all the different components (major and minor)
Fionnuala P O'Connell et al.
Archives of pathology & laboratory medicine, 129(3), 338-347 (2005-03-02)
Breast carcinoma often metastasizes to the gastrointestinal tract, especially the stomach, where it is frequently difficult to distinguish from a primary gastric carcinoma. To evaluate the utility of immunohistochemical stains in differentiating primary gastric carcinomas from metastatic breast carcinomas. Mucosal
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