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安全信息

283M-1

Sigma-Aldrich

HBME-1 (HBME-1) Mouse Monoclonal Antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

HBME-1, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (283M-14)
vial of 0.5 mL concentrate (283M-15)
bottle of 1.0 mL predilute (283M-17)
vial of 1.0 mL concentrate (283M-16)
bottle of 7.0 mL predilute (283M-18)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

同位素/亚型

IgMκ

控制

mesothelioma

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic, membranous

一般描述

Hector Battifora mesothelial-1 (HBME-1) is a membrane antigen that exists in the microvilli ofmesothelial cells and other epithelial cells. Anti-HBME-1 labels thyroid papillary carcinomaand follicular carcinoma but not normal thyroid making it a valuable marker for distinguishingthyroid malignancies from benign thyroid lesions. It has also been demonstrated to labelmesothelial cells, both benign and malignant (malignant mesothelioma), and thus can aid inthe identification of mesothelioma.

质量


IVD

IVD

IVD

RUO

联系

HBME-1 Positive Control Slides, Product No. 283S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J E Barroeta et al.
Endocrine pathology, 17(3), 225-234 (2007-02-20)
Several immunohistochemical markers have been used to aid in the diagnosis of follicular-derived lesions of the thyroid (FDLT). In this study we analyze the diagnostic efficacy of an immunopanel of antibodies to cytokeratin-19 (CK19), galectin-3 (GAL-3), HBME-1, anti-MAP kinase (ERK)
Daniela Cabibi et al.
Thyroid : official journal of the American Thyroid Association, 17(7), 603-607 (2007-08-19)
To verify whether immunohistochemistry might be useful in the distinction between a true laterocervical metastasis of an undetected thyroid carcinoma and a primary tumor outside the gland. Galectin-3, cytokeratin 19, and HBME-1 were assessed in six cases (group A) of
A Coli et al.
Journal of experimental & clinical cancer research : CR, 26(2), 221-227 (2007-08-30)
Ninety-six thyroid lesions were immunohistochemically evaluated for HBME-1 and Galectin-3 expression including nodules with cytological atypia, the latter defined as nuclear features suggestive but not diagnostic of papillary thyroid carcinoma. Thirty nodules with cytological atypia, 49 papillary thyroid carcinomas (PTCs)
A C Bateman et al.
Histopathology, 30(1), 49-56 (1997-01-01)
Histological diagnosis of malignant mesothelioma and differentiation from adenocarcinoma is often difficult. Definitive pathological confirmation of malignant mesothelioma requires demonstration of an appropriate immunohistochemical phenotype. Selection of an optimum panel of immunohistochemical antibodies for the reliable identification of malignant mesothelioma
C C Cheung et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(4), 338-342 (2001-04-13)
In thyroid, the diagnosis of papillary carcinoma (PC) is based on nuclear features; however, identification of these features is inconsistent and controversial. Proposed markers of PC include HBME-1, specific cytokeratins (CK) such as CK19, and ret, the latter reflecting a

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