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Merck
CN
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文件

安全信息

282M-9

Sigma-Aldrich

HMB-45 (HMB-45) Mouse Monoclonal Antibody

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UNSPSC代码:
12352200
NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

HMB-45, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (282M-94)
vial of 0.5 mL concentrate (282M-95)
bottle of 1.0 mL predilute (282M-97)
vial of 1.0 mL concentrate (282M-96)
bottle of 7.0 mL predilute (282M-98)

制造商/商品名称

Cell Marque™

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG1κ

控制

melanoma

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

相关类别

一般描述

Anti-HMB45 is a useful melanoma immunohistochemical marker that reacts with antigenspresent on immature melanosomes. Anti-HMB45 is useful for identifying amelanoticmelanoma from other neoplastic lesions with similar morphology.

质量


IVD
IVD
IVD
RUO

联系

HMB-45 Positive Control Slides, Product No. 282S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

法规信息

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L Weiss et al.
The Journal of pathology, 150(3), 195-203 (1986-11-01)
The sequence of events in haematogenous metastasis from colonic carcinoma was analysed, using 1541 necropsy reports from 16 centres. The findings are consistent with the cascade hypothesis that metastases develop in discrete steps, first in the liver, next in the
An assessment of a melanoma-specific antibody (HMB-45) and other immunohistochemical markers of malignant in paraffin-embedded tissue.
AS-Y Leong, et al.
Surgical Pathology, 2, 137-145 (1989)
M R Wick et al.
Archives of pathology & laboratory medicine, 112(6), 616-620 (1988-06-01)
The efficacy of two new monoclonal antibodies with cell lineage-restricted reactivity (HMB-45 [melanocytes] and anti-synaptophysin [neuroepithelial cells]) was compared with that of "traditional" antibody panels in the delineation of malignant melanoma (MM) of the sinonasal region, nasopharyngeal carcinoma (NPC), and
Helene Nortvig Abrahamsen et al.
Cancer, 100(8), 1683-1691 (2004-04-10)
The optimal technique for sentinel lymph node (SN) assessment in patients with melanoma is controversial. Molecular analysis (reverse transcriptase-polymerase chain reaction) detects significantly greater numbers of SNs with suspected micrometastases (up to 71%) than does routine histopathology (approximately 20%). The
L Vaggelli et al.
Tumori, 86(4), 346-348 (2000-10-04)
Elective lymph node dissection (ELND) for patients with malignant melanoma is still controversial. A possible alternative could be biopsy of the first tumor draining lymph node, the sentinel node (SN), which can be identified by means of radionuclide techniques. Our
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