跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

27689

Sigma-Aldrich

刀豆素A

from Streptomyces sp., ≥80% (HPLC)

别名:

福霉素

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C46H75NO14
CAS号:
80890-47-7
分子量:
866.09
Beilstein:
3560277
MDL编号:
MFCD00210037
UNSPSC代码:
12352200
PubChem化学物质编号:
329753012
NACRES:
NA.25

生物来源

Streptomyces sp.

质量水平

100

方案

≥80% (HPLC)

表单

solid

抗生素抗菌谱

viruses

作用机制

enzyme | inhibits

储存温度

−20°C

SMILES字符串

CCC1C(O)C(C)C\C(C)=C\C=C\C(OC)C(OC(=O)\C(OC)=C\C(C)=C\C(C)C1O)C(C)C(O)C(C)[C@]2(O)C[C@@H](O[C@H]3C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O3)[C@H](C)C(O2)\C=C\C

InChI

1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26?,27?,28-,29?,30?,31-,32?,33-,34?,35?,37-,38+,39?,40?,41?,42?,43-,46+/m1/s1

InChI key

DJZCTUVALDDONK-LWLXYWDNSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

Chemical structure: macrolide

应用

Concanamycin A has been used as an inhibitor of the perforin pathway.

其他说明

Characterization of concanamycins A, B and C; Selective inhibitor of the vacuolar proton-ATPase.

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Irrit. 2

储存分类代码

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
BCCG2615
BCCF5240
BCCB6236
BCBV8057
BCBZ4846

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

H. Kinashi et al.
The Journal of Antibiotics, 38, 1333-1333 (1984)
R Guinea et al.
FEBS letters, 349(3), 327-330 (1994-08-08)
The selective inhibitor of the vacuolar proton-ATPase, concanamycin A, powerfully blocks influenza virus entry into cells, if present during the initial times of virus infection. Attachment of virus particles to cells is not prevented by concanamycin A, rather the exit
Cytotoxic mechanisms in different forms of T-cell-mediated drug allergies
P. C. Kuechler
Allergy (2004)
Concanamycin A, the specific inhibitor of V-ATPases, binds to the V(o) subunit c.
Huss M
The Journal of Biological Chemistry, 277(43), 40544-40548 (2002)
Seléne van der Poel et al.
Traffic (Copenhagen, Denmark), 12(11), 1634-1647 (2011-08-04)
Sphingolipids are considered to play a key role in protein sorting and membrane trafficking. In melanocytic cells, sorting of lysosomal and melanosomal proteins requires the sphingolipid glucosylceramide (GlcCer). This sorting information is located in the lumenal domain of melanosomal proteins.
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门