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26978

Sigma-Aldrich

氯化胆碱

BioUltra, ≥99.0% (AT)

别名:

(2-羟乙基)三甲基氯化铵

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About This Item

线性分子式:
(CH3)3N(Cl)CH2CH2OH
CAS号:
67-48-1
分子量:
139.62
Beilstein:
3563126
EC 号:
200-655-4
MDL编号:
MFCD00011721
UNSPSC代码:
12352211
PubChem化学物质编号:
57648187
NACRES:
NA.25
方案:
≥99.0% (AT)
表单:
powder or crystals
溶解性:
H2O: 1 M, clear, colorless

生物来源

synthetic

质量水平

200

产品线

BioUltra

方案

≥99.0% (AT)

表单

powder or crystals

杂质

insoluble matter, passes filter test

颜色

colorless to white

pH值（酸碱度）

5.0-7.5 (25 °C, 1 M in H2O)

mp

302-305 °C (dec.) (lit.)

溶解性

H2O: 1 M, clear, colorless

痕量阴离子

sulfate (SO42-): ≤50 mg/kg

痕量阳离子

Al: ≤5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

紫外吸收

λ: 260 nm Amax: 0.015
λ: 280 nm Amax: 0.010

SMILES字符串

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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相关类别

生化/生理作用

胆碱是一种必需营养素，通常与B族复合维生素组合，在许多生物过程中发挥关键作用。

底物

胆碱乙酰基转移酶底物

其他说明

恢复剥除皮质大鼠的纹状体的胆碱能、生化和药理活性
销售限制可能适用

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

Lot/Batch Number
BCCD5136
BCCK4897
BCCB4887
BCCB1686
BCCF2138

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S Consolo et al.
Journal of neurochemistry, 54(2), 571-577 (1990-02-01)
Interruption of the corticostriatal pathway by undercutting the frontal cortex resulted after 2 weeks in a 40% reduction of basal acetylcholine (ACh) release in vivo, and in inhibition of the striatal sodium-dependent high-affinity uptake of choline (SDHACU) to the same
Sotirios Chondrogiannis et al.
European journal of nuclear medicine and molecular imaging, 40(9), 1356-1364 (2013-05-15)
The aims of the study were (a) to evaluate the diagnostic role, by means of positive detection rate (PDR), of ¹⁸F-choline (CH) positron emission tomography (PET)/CT in patients with prostate cancer treated with radiotherapy, with curative intent, and suspicion of
Elisabeth Traiffort et al.
Molecular aspects of medicine, 34(2-3), 646-654 (2013-03-20)
The Na(+)-independent, high affinity choline carrier system proposed to supply choline for the synthesis of cell membrane phospholipids was recently associated with SLC44 family members (SLC44A1-5) also called choline-like transporter family. SLC44A1 is widely expressed throughout the nervous system in
Mohsen Beheshti et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(6), 833-840 (2013-04-06)
We evaluated the potential of (18)F-fluoromethyldimethyl-2-hydroxyethyl-ammonium (FCH) PET/CT in the detection of recurrent disease or distant metastases and correlated its diagnostic accuracy with prostate-specific antigen (PSA) levels in prostate cancer patients with biochemical evidence of recurrence. Furthermore, the influences of
Zhuo Li et al.
Biochimica et biophysica acta, 1840(7), 2112-2122 (2014-03-19)
Choline kinase has three isoforms encoded by the genes Chka and Chkb. Inactivation of Chka in mice results in embryonic lethality, whereas Chkb(-/-) mice display neonatal forelimb bone deformations. To understand the mechanisms underlying the bone deformations, we compared the
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