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Merck
CN

235R-1

CDX-2 (EPR2764Y) Rabbit Monoclonal Primary Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203

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biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EPR2764Y, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (235R-14)
vial of 0.5 mL concentrate (235R-15)
bottle of 1.0 mL predilute (235R-17)
vial of 1.0 mL concentrate (235R-16)
bottle of 7.0 mL predilute (235R-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

colon

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Quality Level

100
500

Gene Information

human ... CDX2(1045)

相关类别

Analysis Note


IVD
IVD
IVD
RUO

General description

CDX-2 is a caudal-related homeobox transcription factor that plays a role in the development and maintenance of intestinal mucosa. This protein is expressed in the normal and neoplastic gastrointestinal epithelium, including colorectal adenocarcinoma. It is useful for identifying the gastrointestinal origin of benign and malignant lesions.

Other Notes

CDX-2 Positive Control Slides, Product No. 235S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000485751
0000474295
0000474295
0000485751
0000482018

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Gabriel M Groisman et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 23(1), 52-57 (2003-12-12)
Histologic differentiation of primary ovarian carcinoma from colonic carcinoma metastatic to the ovary may be difficult. Cytokeratin 7 (CK7) and cytokeratin 20 (CK20) immunostaining is usually used, but these markers lack specificity for ovarian and intestinal epithelium, and overlapping results
Lori A Erickson et al.
Endocrine pathology, 15(3), 247-252 (2005-01-11)
The transcription factors CDX1 and CDX2 are homeobox genes that regulate development of the epithelium of the small and large intestine. A few studies have shown that Cdx2 protein expression is useful in the diagnosis of adenocarcinomas as well as
Anjali Saqi et al.
American journal of clinical pathology, 123(3), 394-404 (2005-02-18)
Carcinoids of different organs appear morphologically indistinguishable. We studied the usefulness of differential expression of CDX2 and thyroid transcription factor-1 (TTF-1) in 78 gastrointestinal and pulmonary carcinoids and their metastases (n = 10). CDX2 staining of gastric biopsy specimens with
Robert M Mazziotta et al.
Applied immunohistochemistry & molecular morphology : AIMM, 13(1), 55-60 (2005-02-22)
Paraffin-embedded sections of various adenocarcinomas (13 colonic, 11 mucinous ovarian, 5 serous ovarian, 8 pancreatic, 6 ampullary, 12 gastric, 5 esophageal, 10 endometrial, 29 breast, and 55 lung) and 29 additional lung carcinomas (nonadenocarcinomas) were immunostained with antibodies to CDX2
Reda S Saad et al.
American journal of clinical pathology, 122(3), 421-427 (2004-09-15)
We studied the diagnostic value of Cdx2 to distinguish mucinous bronchioloalveolar carcinoma from mucinous colorectal adenocarcinoma metastatic to the lung. We retrieved 92 via the hospital computer system, including 30 mucinous bronchioloalveolar carcinomas, 32 nonmucinous bronchioloalveolar carcinomas, and 30 mucinous
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