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Merck
CN

22640

Sigma-Aldrich

奎宁 半硫酸盐 一水合物

suitable for fluorescence, BioReagent, 99.0-101.0%

别名:

Quinine sulfate (2:1) (salt) dihydrate

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About This Item

经验公式(希尔记法):
C20H24N2O2 · 0.5H2O4S · H2O
分子量:
391.47
Beilstein:
6113937
MDL编号:
UNSPSC代码:
12352210
PubChem化学物质编号:
NACRES:
NA.32

产品线

BioReagent

质量水平

检测方案

99.0-101.0%

mp

~225 °C (dec.) (lit.)

荧光

λex 347 nm; λem 448 nm in 0.5 M sulfuric acid

适用性

suitable for fluorescence

抗生素抗菌谱

parasites

作用机制

enzyme | inhibits

SMILES字符串

O.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5

InChI

1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1

InChI key

ZHNFLHYOFXQIOW-LPYZJUEESA-N

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相关类别

一般描述

Quinine hemisulfate salt monohydrate is a naturally occurring well known fluorescent standard material. Quinine hemisulfate salt monohydrate or QSM has a fluorescence lifetime between 1.0 to 3.0 ns.

应用

Quinine hemisulfate salt monohydrate is used for indirect photometric detection of polyamines in biological samples. It is suitable for studying metabolism of bio crystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

生化/生理作用

钾通道阻滞剂。抗疟疾、抗胆碱能、抗高血压和降血糖剂;最初从南美树木的金鸡纳科中分离出来的生物碱。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

分析证书(COA)

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Yuting Bai et al.
Nanoscale research letters, 13(1), 287-287 (2018-09-19)
Carbon dots (CDs) are a member of fluorescent carbon nanomaterials that are widely applied in bioimaging, photothermal therapy (PTT), and biosensors for its tunable fluorescence, photothermal conversion property, and excellent biocompatibility. Surface passivation and doping especially the doping of N
Marta Pokrzywnicka et al.
Talanta, 82(1), 422-425 (2010-08-06)
In this paper a concept of very simple measurement system dedicated for simultaneous photometric and fluorometric detection is presented. Only three ordinary unmodified light emitting diodes (LEDs) can be applied in this analytical device: one of them is used in
S D Pack et al.
Optics letters, 23(15), 1215-1217 (2007-12-19)
We report on a novel laser-induced fluorescence triple-integration method (LIFTIME) that is capable of making rapid, continuous fluorescence lifetime measurements by a unique photon-counting technique. The LIFTIME has been convolved with picosecond time-resolved laser-induced fluorescence, which employs a high-repetition-rate mode-locked
Y Ma et al.
Journal of chromatography, 608(1-2), 93-96 (1992-09-11)
A rapid separation of polyamines and some related amino acids in cultured tumor cells by high-performance capillary zone electrophoresis with indirect photometric detection is demonstrated. 60 cm x 75 microns I.D. fused-silica capillary was used for the separation and quinine
Elaine B Bohórquez et al.
Malaria journal, 11, 350-350 (2012-10-24)
The naturally fluorescent compound quinine has long been used to treat malaria infections. Although some evidence suggests that quinine acts in the parasite food vacuole, the mechanism of action of quinine has not yet been resolved. The Plasmodium falciparum multidrug

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