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安全信息

225M-1

Sigma-Aldrich

BCA-225 (Cu-18) Mouse Monoclonal Antibody

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UNSPSC代码:
12352200
NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

Cu-18, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (225M-14)
vial of 0.5 mL concentrate (225M-15)
bottle of 1.0 mL predilute (225M-17)
vial of 1.0 mL concentrate (225M-16)
bottle of 7.0 mL predilute (225M-18)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

同位素/亚型

IgG1

控制

breast

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

一般描述

Anti-BCA-225 antibody recognizes a human breast carcinoma associated glycoprotein BCA-225 (220-225kD). This protein differs in size and distribution from other breast carcinoma antigens. Unlike other antibodies against breast carcinoma antigens, this antibody does not react with benign or malignant colonic, stomach, prostate, liver, pancreas, thyroid, or parotid tissues. Adenocarcinomas of the lung, ovary and endometrium also stain with this antibody.

质量


IVD

IVD

IVD

RUO

联系

BCA-225 Positive Control Slides, Product No. 225S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

法规信息

监管及禁止进口产品

分析证书(COA)

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R Mesa-Tejada et al.
The American journal of pathology, 130(2), 305-314 (1988-02-01)
A glycoprotein, BCA-225 (Mr 225,000-250,000), has been identified in cells and spent medium of clone 11 T47D breast carcinoma cells by three murine monoclonal antibodies, CU18, CU26, and CU46. The antigen was localized in paraffin sections of 167/178 (94%) Bouin's-fixed
T S Loy et al.
American journal of clinical pathology, 96(3), 326-329 (1991-09-01)
BCA-225 is a glycoprotein identified in human breast carcinoma cells that has been reported to show a restricted distribution in other human tissues. To further define the presence of BCA-225 in human carcinomas, the authors performed an immunohistochemical study, applying
Monoclonal Antibodies and Breast Cancer (1985)
C K Ma et al.
American journal of clinical pathology, 99(5), 551-557 (1993-05-01)
Distinguishing primary hepatocellular carcinoma (HCC) from metastatic carcinomas to the liver is often difficult, if not impossible, particularly in needle biopsy and fine-needle aspiration specimens. In an attempt to identify a specific immunohistochemical profile that would distinguish HCC from metastatic

商品

免疫组织化学(免疫组化,IHC)用于表征所有组织中的细胞内蛋白质或各种细胞表面。个体标记,或更常用的各种标记蛋白质组,可用于表征各种肿瘤亚型,确定原发组织,区分转移性肿瘤和原发性肿瘤,并提供可能对预后有重要意义、预测对治疗的响应、或评估残留肿瘤后处理的其他信息。

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