所有图片(1)
About This Item
经验公式（希尔记法）:
C12H15N3O3S
CAS号:
分子量:
281.33
Beilstein:
677664
MDL编号:
UNSPSC代码:
51101500
PubChem化学物质编号:
推荐产品
方案
≥98% (HPLC)
表单
powder
颜色
colorless to white
抗生素抗菌谱
neoplastics
parasites
作用机制
DNA synthesis | interferes
enzyme | interferes
protein synthesis | interferes
SMILES字符串
CCCS(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1
InChI
1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI key
VXTGHWHFYNYFFV-UHFFFAOYSA-N
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一般描述
化学结构：苯并咪唑
应用
利苯达达唑是具有广谱驱虫活性的氨基甲酸甲酯苯并咪唑。阿糖达唑是阿苯达唑的关键代谢产物。研究表明它可能通过使细胞周期停滞在G2/M 期而诱导人癌细胞 HT-29 凋亡。
生化/生理作用
罗苯达唑是阿苯达唑的关键代谢产物，并作为驱虫药。研究表明，它可能通过使细胞周期停滞在 G2/M 期而诱导人癌细胞 HT-29 凋亡。
包装
25G
其他说明
将容器密闭保存在干燥和通风良好的地方。在干燥处保存。
警示用语：
Warning
危险分类
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1 - STOT RE 2 Oral
靶器官
Adrenal gland,spleen,male reproductive organs,Blood
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Mohammad H Pourgholami et al.
Cancer chemotherapy and pharmacology, 55(5), 425-432 (2004-11-27)
The peritoneal surface remains an important failure site for patients with colorectal cancer. We have recently shown that albendazole (ABZ), a safe and effective anthelmintic drug, has profound antitumor activity in hepatocellular cancer. Furthermore, albendazole also possesses unique physiochemical and
Gracia Merino et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(5), 614-618 (2005-02-11)
Methylcarbamate benzimidazoles [albendazole (ABZ), fenbendazole (FBZ), and their respective sulfoxide derivatives, albendazole sulfoxide (ABZSO) and oxfendazole (OXF)] are therapeutically important anthelmintic agents with low bioavailability. We studied their in vitro interaction with the apical ATP-binding cassette (ABC) drug efflux transporters
Viviane Cangerana Hilário et al.
Journal of pharmaceutical and biomedical analysis, 61, 100-107 (2012-01-11)
A high-performance liquid chromatographic method using polar organic mode was developed to analyze albendazole (ABZ), albendazole sulfone (ABZSO(2)) and the chiral and active metabolite albendazole sulfoxide (ABZSOX, ricobendazole) that was further applied in stereoselective fungal biotransformation studies. The chromatographic separation
Hana Bártíková et al.
Veterinary parasitology, 176(1), 27-33 (2010-11-16)
Albendazole (ABZ) is one of the most important benzimidazole compounds possessing high activity against the lancet fluke, Dicrocoelium dendriticum. ABZ sulphoxide (ABZ.SO) is the main molecule present in the bloodstream of an ABZ-treated host. The aim of this study was
Daniel B Carrão et al.
Electrophoresis, 32(19), 2746-2756 (2011-09-10)
Hollow fiber liquid-phase microextraction and CE were applied for the determination of albendazole sulfoxide (ASOX) enantiomers in liquid culture medium after a fungal biotransformation study. The analytes were extracted from 1 mL of liquid culture medium spiked with the internal
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