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Merck
CN

19699

Sigma-Aldrich

-2-癸烯酸

≥95.0% (HPLC)

别名:

2-Decenoic acid, (2Z)-

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About This Item

经验公式(希尔记法):
C10H18O2
CAS号:
分子量:
170.25
Beilstein:
1721990
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25

质量水平

方案

≥95.0% (HPLC)
95.0-105.0% (T)

表单

liquid

官能团

carboxylic acid

脂质类型

unsaturated FAs

储存温度

−20°C

SMILES字符串

CCCCCCC\C=C/C(O)=O

InChI

1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-

InChI key

WXBXVVIUZANZAU-HJWRWDBZSA-N

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应用

-2-癸烯酸可用于研究其对人 HepG2 细胞系的细胞毒性作用。它还用于研究其协同抗螺旋体作用。

生化/生理作用

-2--癸烯酸是一种由铜绿假单胞菌产生的脂肪酸信使(信号分子)。它具有抗生物膜特性并可将大部分细胞转化为浮游(自由游动)表型。-2-癸烯酸保留了细菌对抗菌剂的敏感性。它对人体细胞没有任何毒性,因此可用于治疗生物膜相关感染。-2--癸烯酸即使在纳摩尔范围内也具有活性。它介导休眠的铜绿假单胞菌大肠杆菌向其生物活性状态转变,同时不影响细胞数量。-2-癸烯酸与抗菌剂一起使用时,对大肠杆菌和肺炎克雷伯菌混菌生物膜有效。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 1


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Thomas Tørring et al.
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Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative gammaproteobacterial pathogen that infects and intracellularly replicates in human macrophages and a variety of protozoa. L. pneumophila encodes an orphan biosynthetic gene cluster (BGC) that contains isocyanide-associated biosynthetic genes and
Azadeh Rahmani-Badi et al.
Archives of oral biology, 60(11), 1655-1661 (2015-09-10)
To investigate the ability of cis-2-decenoic acid (C2DA) to induce dispersion in single-species biofilms formed by Streptococcus mutans and Candida albicans, as well as to remove their bacterial-fungal dual-species biofilms when combined with low concentrations of chlorhexidine (CHX). For biofilm
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Two series of novel 5-arylazo-3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galacto pyranosyloxy) pyridines and 3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galactopyranosyloxy) pyridines were synthesized in high yields utilizing a microwave-assisted synthesis tool guided by the principles of green chemistry. The chemical structures of the new substances were confirmed on the basis of
A Goc et al.
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Little is known about the effects of phytochemicals against Borrelia sp. causing Lyme disease. Current therapeutic approach to this disease is limited to antibiotics. This study examined the anti-borreliae efficacy of several plant-derived compounds and micronutrients. We tested the efficacy
A Goc et al.
Journal of applied microbiology, 123(3), 637-650 (2017-06-24)
Borrelia sp., a causative pathogenic factor of Lyme disease (LD), has become a major public health threat. Current treatments based on antibiotics often lead to relapse after their withdrawal. Naturally derived substances that could work synergistically to display higher efficacy

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