质量水平
检测方案
≥98.0% (HPLC)
形式
(Liquid or Viscous Liquid)
颜色
colorless to green-yellow
colorless to green
colorless to yellow
储存温度
−20°C
SMILES字符串
O=C1C2(C/C=C(C)/CCCC(C)CCCC(C)CCCC(C)C)C(O2)(C)C(C3=CC=CC=C31)=O
InChI
1S/C31H46O3/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-31-29(33)27-19-8-7-18-26(27)28(32)30(31,6)34-31/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+
InChI key
KUTXFBIHPWIDJQ-LKUDQCMESA-N
生化/生理作用
维生素K1 2,3-环氧化物是一种维生素K衍生物。它是一种由植物产生的脂溶性维生素。维生素K是必不可少的凝血物质。人类膳食很少缺乏维生素K，因其会在体内细胞中不断循环。维生素K 2,3-环氧化物可作为维生素K 2,3-环氧化物还原酶 (VKOR) 复合体的底物。患者血清中维生素K环氧化物浓度的上升与家族性多发性凝血因子缺乏症有关。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
D Trenk et al.
Journal of clinical pharmacology, 30(8), 737-742 (1990-08-01)
It seems that cephalosporins bearing a N-methyl-thio-tetrazole or a methyl-thiadiazole moiety in their molecule can cause hypoprothombinemia in patients via inhibition of the metabolism of vitamin K1 if they are in addition in a vitamin K1-deficient state. The authors therefore
Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis
Shearer MJ and Newman P
Journal of Lipid Research, 55(3), 345-362 (2014)
Changes in the urinary metabolites of phylloquinone (vitamin K1) in man following therapeutic anticoagulation with warfarin.
A McBurney et al.
Biochemical pharmacology, 27(3), 273-278 (1978-02-01)
K Hirauchi et al.
Journal of chromatography, 430(1), 21-29 (1988-08-19)
A highly sensitive method for measuring endogenous vitamin K1, menaquinone-4 (which is one of the K2 vitamins) and vitamin K1 2,3-epoxide in human plasma was developed, based on high-performance liquid chromatography with coulometric reduction and fluorimetric detection, following extraction from
Metabolism of vitamin K1 (phylloquinone) in man
Barkhan P and Shearer MJ
Proceedings of the Royal Society of Medicine (1977)
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