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Merck
CN

19608

Sigma-Aldrich

Thiocellobiose

≥98.0% (TLC)

别名:

4-S-β-D-glucopyranosyl-4-thio-D-glucose

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About This Item

经验公式(希尔记法):
C12H22O10S
CAS号:
分子量:
358.36
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

方案

≥98.0% (TLC)

表单

solid

技术

thin layer chromatography (TLC): suitable

储存温度

−20°C

SMILES字符串

OC[C@@H](O)[C@@H](S[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

InChI

1S/C12H22O10S/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12-/m0/s1

InChI key

VMEDEPBFFWJMMG-WELRSGGNSA-N

应用

Thiocellobiose is a glucose disaccharide linked via a β(1-4) thioether bond. Thiocellobiose is a cellulase inducer and inhibitor useful to identify, differentiate and characterize cellobiose-active β-glucosidase(s). Thiocellobiose is also used as a substrate to identify, differentiate and characterize cellobiose dehydrogenase(s).

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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U Baminger et al.
Applied and environmental microbiology, 67(4), 1766-1774 (2001-04-03)
Cellobiose dehydrogenase (CDH) is an extracellular hemoflavoenzyme produced by several wood-degrading fungi. In the presence of a suitable electron acceptor, e.g., 2,6-dichloro-indophenol (DCIP), cytochrome c, or metal ions, CDH oxidizes cellobiose to cellobionolactone. The phytopathogenic fungus Sclerotium rolfsii (teleomorph: Athelia
G Henriksson et al.
Biochimica et biophysica acta, 1383(1), 48-54 (1998-04-18)
Substrate structural mapping suggests that the catalytic site of cellobiose dehydrogenase from Phanerochaete chrysosporium forms a narrow cave with two hexose binding subsites. Kinetic data also show that beta-di or oligosaccharides are favored electron donors with respect to both KM
E Montero et al.
FEBS letters, 421(3), 243-248 (1998-02-19)
The conformation of 4-thiocellobiose bound to beta-glucosidase from Streptomyces sp. has been studied by 1H-NMR transferred nuclear Overhauser effect spectroscopy (TR-NOE). Thiocellobiose behaves as an inhibitor of this glucosidase when cellobiose is used as substrate. NOE measurements and molecular mechanics
Meera E Atreya et al.
Biotechnology and bioengineering, 113(2), 330-338 (2015-08-25)
Enzymes that degrade cellulose into glucose are one of the most expensive components of processes for converting cellulosic biomass to fuels and chemicals. Cellulase enzyme Cel7A is the most abundant enzyme naturally employed by fungi to depolymerize cellulose, and like
Pablo Isorna et al.
Journal of molecular biology, 371(5), 1204-1218 (2007-06-26)
Bacteria species involved in degradation of cellulosic substrates produce a variety of enzymes for processing related compounds along the hydrolytic pathway. Paenibacillus polymyxa encodes two homologous beta-glucosidases, BglA and BglB, presenting different quaternary structures and substrate specificities. We previously reported

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