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Merck
CN
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文件

17927

Sigma-Aldrich

9-氧代-10 (9 H )-吖啶乙酸

for HPLC derivatization, ≥99.0% (T)

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别名:
10-（羧甲基）-9 (10H) 吖啶酮, （9,10-二氢-9-氧代-10-吖啶基）乙酸
经验公式（希尔记法）:
C15H11NO3
CAS号:
38609-97-1
分子量:
253.25
Beilstein:
227508
MDL编号:
MFCD00157050
UNSPSC代码:
12352106
PubChem化学物质编号:
329751585
NACRES:
NA.32

等级

for HPLC derivatization

质量水平

100

检测方案

≥99.0% (T)

形式

solid

mp

~289 °C (dec.)

SMILES字符串

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

InChI key

UOMKBIIXHQIERR-UHFFFAOYSA-N

应用

9-氧-10 (9H)-吖啶乙酸及其类似物被用于研究其作为干扰素诱导剂的潜在活性。

其他说明

HPLC 中荧光测定用氨基酸柱前衍生化试剂；药剂学基础

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WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)
E D Bazhanova
Eksperimental'naia i klinicheskaia farmakologiia, 75(10), 42-46 (2012-12-18)
A detailed analysis of the literature data gives contradictory information about the role of interferon-alpha in the regulation of apoptosis, while there are almost no data on the participation of cycloferon in this process. Results of original experiments in recent
S.A. Lyakhov et al.
Pharmazie, 49, 367-367 (1994)
A V Gordeets et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(2), 17-19 (2013-05-02)
The case records of 120 children older than 4 years with rotavirus infection have been studied. In this group, 22 patients received basic therapy and 98 received complex therapy with cycloferon. Appropriate therapy resulted in rapid positive dynamics of clinical
Tolerance or hyperreactivity to interferon induction by sodium salt of 9-oxo-10-acridineacetic acid and analogs in mice and in the mouse macrophage cultures.
Szulc B, Inglot AD, Inglot O.
Arch. Immunol. Ther. Exp., 35, 389-395 (1987)
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