Quality Level
density
1.01 g/mL at 20 °C
storage temp.
2-8°C
SMILES string
Cl[Co]Cl
InChI
1S/2ClH.Co/h2*1H;/q;;+2/p-2
InChI key
GVPFVAHMJGGAJG-UHFFFAOYSA-L
Application
0.1M 氯化钴溶液已被用于模拟前列腺癌细胞的低氧暴露和 HIF-1（缺氧诱导因子 1）的表达。其已用于诱导人肠上皮细胞缺氧。
Biochem/physiol Actions
氯化钴通过上调缺氧诱导因子-1α 诱导细胞缺氧 (HIF-1α)、促红细胞生成素和糖酵解酶。它也是大鼠神经元 PC12 细胞线粒体 DNA 损伤的原因。其也负责诱导细胞凋亡。
0.1M 氯化钴溶液是添加剂筛选试剂盒的添加剂筛选液。添加剂筛选试剂盒设计用于快速方便地评价添加剂及其影响样品结晶的能力。添加剂试剂盒为精制结晶条件提供了工具。
0.1M 氯化钴溶液是添加剂筛选试剂盒的添加剂筛选液。添加剂筛选试剂盒设计用于快速方便地评价添加剂及其影响样品结晶的能力。添加剂试剂盒为精制结晶条件提供了工具。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Carc. 1B - Repr. 1B
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells.
Wang G, et al.
Nucleic Acids Research, 28, 2135-2135 (2000)
CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells.
Zeno S, et al.
Biochemistry, 48, 4652-4652 (2009)
Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.
Wojtal KA, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 307, G673-G673 (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 15862-1ML-F | 04061838744081 |