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安全信息

131R-2

Sigma-Aldrich

CD31 (EP78) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP78, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

表单

buffered aqueous solution

种属反应性

human

包装

bottle of 1.0 mL predilute (131R-27)
bottle of 7.0 mL predilute (131R-28)
vial of 0.1 mL concentrate (131R-24)
vial of 0.5 mL concentrate (131R-25)
vial of 1.0 mL concentrate (131R-26)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG

运输

wet ice

储存温度

2-8°C

基因信息

human ... PECAM1(5175)

一般描述

CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Endothelial cells also express this marker; therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms.1-3 Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells.4 Staining of nonvascular tumors (excluding hematopoietic neoplasms) has not been observed.

质量


IVD

IVD

IVD

RUO

联系

CD31 Positive Control Slides, Product No. 131S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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B R De Young et al.
American journal of clinical pathology, 110(3), 374-377 (1998-09-05)
CD31 is a specific and sensitive marker of endothelial differentiation. Previous reports have described its immunoreactivity in large series of soft tissue neoplasms, as well as its comparison with other available and commonly used endothelial markers. CD31 reactivity in carcinomas
F Alexander-Sefre et al.
Journal of clinical pathology, 56(10), 786-788 (2003-09-30)
Lymphovascular space invasion (LVSI) is an important step in the complex process of tumour metastasis. Various methods have been used in the past to improve the histological detection of LVSI. To develop a sensitive immunohistochemical method for the detection of
J U Alles et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(2), 209-214 (1986-02-01)
A new monoclonal antibody (moab BW 200) of IgG3 kappa-isotype was generated which recognizes an epitope located on an antigen molecule restricted to human neoplastic and non-neoplastic endothelial cells. The molecular weight of the antigen was determined using immunoprecipitation analysis
D V Parums et al.
Journal of clinical pathology, 43(9), 752-757 (1990-09-01)
A new monoclonal antibody, JC70, raised against a membrane preparation from a spleen affected by hairy cell leukaemia, recognises a membrane bound glycoprotein identical with that of the CD31 group of monoclonal antibodies. The antibody stains a fixation resistant epitope

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