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Merck
CN

131M-9

CD31 (JC70)

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

JC70, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (131M-94)
vial of 0.5 mL concentrate (131M-95)
bottle of 1.0 mL predilute (131M-97)
vial of 1.0 mL concentrate (131M-96)
bottle of 7.0 mL predilute (131M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1κ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic, membranous

Quality Level

Gene Information

human ... PECAM1(5175)

General description

CD31,或称血小板-内皮细胞粘附分子-1(PECAM-1),是一种血管细胞粘附和信号传导分子,在维持内皮细胞连接处的血管通透性障碍方面起一定作用。CD31 的免疫组织化学检测表明其在非肿瘤和肿瘤血管内皮细胞中的细胞质和细胞膜表达,包括血管源性肿瘤,如血管瘤和血管肉瘤。

Other Notes

CD31 阳性对照玻片,货号 131S,可用于免疫组化(福尔马林固定、石蜡包埋的切片)。
有关技术服务,请联系: 800-665-7284或电子邮件:service@cellmarque.com

Physical form

溶于Tris缓冲液中的溶液(pH 7.3-7.7),含1%BSA和 <0.1%叠氮化钠

Preparation Note

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Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R L Attanoos et al.
Thorax, 55(10), 860-863 (2000-09-19)
Three cases of diffuse malignant vascular tumours of the pleura are described which mimicked malignant mesothelioma clinically and pathologically (so called "pseudomesothelioma"). All had occupational histories of exposure to asbestos. The relationship of these tumours to mesothelioma and asbestos exposure
Malak Abedalthagafi et al.
Annals of diagnostic pathology, 14(1), 15-22 (2010-02-04)
Cutaneous angiosarcoma (AS) is a rare malignant neoplasm of dermis composed of infiltrating cells of endothelial phenotype with overall poor prognosis. Although autocrine stimulation by vascular endothelial growth factor secretion may play a role in the pathogenesis of angiosarcoma, its
Xiu-Lian Xu et al.
The American Journal of dermatopathology, 32(8), 837-840 (2010-10-01)
Microvenular hemangioma (MVH) is an uncommon benign vascular neoplasm that usually occurs as a solitary asymptomatic red or purple papule, nodule, or plaque with a predilection for the upper extremities. Patients with more than 1 lesion, that is, multiple MVHs
CD31: An Immunospecific Marker for Endothelial Differentiation in Human Neoplasms
DeYoung BR, et al.
Appl. Immunohistochem., 1, 97-100 (1993)
F Alexander-Sefre et al.
Journal of clinical pathology, 56(10), 786-788 (2003-09-30)
Lymphovascular space invasion (LVSI) is an important step in the complex process of tumour metastasis. Various methods have been used in the past to improve the histological detection of LVSI. To develop a sensitive immunohistochemical method for the detection of

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