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主要文件

12247

Sigma-Aldrich

橄榄苦苷

≥98.0%

别名:

(2S,3E,4S)-3-亚乙基-2-(β-D-葡吡喃糖氧基)-3,4-二氢-5-(甲氧羰基)-2 H-吡喃-4-乙酸 2-(3,4-二羟苯基)乙酯

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25 MG
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25 MG
¥1,974.51

About This Item

经验公式(希尔记法):
C25H32O13
CAS号:
分子量:
540.51
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.32

¥1,974.51


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质量水平

方案

≥98.0%

杂质

≤5.0% water

应用

metabolomics
vitamins, nutraceuticals, and natural products

SMILES字符串

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3

InChI

1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1

InChI key

RFWGABANNQMHMZ-ZCHJGGQASA-N

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此商品
S7576PHR1591A7986
Shikonin ≥98% (HPLC)

S7576

Shikonin

Atovaquone Pharmaceutical Secondary Standard; Certified Reference Material

PHR1591

Atovaquone

Atovaquone ≥98% (HPLC)

A7986

Atovaquone

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

form

powder

form

powder or solid

form

-

form

powder

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: soluble, chloroform: soluble

solubility

methanol: 1 mg/mL

solubility

-

solubility

DMSO: >10 mg/mL

一般描述

橄榄苦苷是橄榄叶提取物中发现的主要次生代谢产物。[1]它是一种环烯醚萜多酚,其结构由烯烯酸与羟酪醇的糖基化酯组成。[1]

应用

橄榄苦苷已被用于:
  • 作为一种抗炎和抗氧化剂,在高脂饮食(HFD)喂养的小鼠肝脏脂肪变性[2]
  • 评估雄性小鼠生殖功能的保护作用及抗氧化特性[3]
  • 研究其对细菌(大肠杆菌)ATP合酶的抑制作用[4]
  • 作为纤溶酶原激活物抑制剂-1 (PAI-1)的抑制剂,检测其对乳腺癌细胞增殖的影响[5]

生化/生理作用

橄榄苦苷具有抗癌、抗微生物、抗病毒、抗缺血和降血脂活性。对皮肤起保护作用,有助于抗衰老。橄榄苦苷还有抗血小板聚集、降压、抗风湿、解热、利尿和血管舒张作用。降低患冠状动脉疾病的风险。[6]橄榄苦苷能促进分泌去甲肾上腺素和肾上腺素。 [7]

包装

无底玻璃瓶。内容物在插入的熔锥内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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    Carla Marchetti et al.
    Evidence-based complementary and alternative medicine : eCAM, 2015, 908493-908493 (2015-12-23)
    Malignant mesothelioma is a poor prognosis cancer in urgent need of alternative therapies. Oleuropein, the major phenolic of olive tree (Olea europaea L.), is believed to have therapeutic potentials for various diseases, including tumors. We obtained an oleuropein-enriched fraction, consisting
    Amon Amini et al.
    International journal of biological macromolecules, 101, 153-164 (2017-03-23)
    The naturally occurring olive phenolics tyrosol, hydroxytyrosol, dihydroxyphenylglycol (DHPG), and oleuropein are known to have antioxidant, antitumor, and antibacterial properties. In the current study, we examined whether the antimicrobial properties of tyrosol, hydroxytyrosol, DHPG, and oleuropein were linked to the
    Oleuropein overrides liver damage in steatotic mice
    Santini SJ, et al.,
    Journal of functional foods, 65, 103756-103756 (2020)
    Ayoob Rostamzadeh et al.
    Heliyon, 6(4), e03785-e03785 (2020-04-28)
    Spermatogenesis is a complicated process in which sperm is susceptible to various chemotherapy drugs such as cyclophosphamide (CP). As olive leaf extract (OLE) and its active ingredient, oleuropein, have variousantioxidant, anti-apoptotic, and anti-inflammatory properties the aim of the present study
    Ioanna Andreadou et al.
    The Journal of nutrition, 136(8), 2213-2219 (2006-07-22)
    Thgoal of this study was to evaluate the efficacy of the antioxidant olive constituent, oleuropein, on infarct size, oxidative damage, and the metabolic profile in rabbits subjected to ischemia. Oleuropein, 10 or 20 mg/(kg x d), was administered to 8

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