推荐产品
生物来源
mouse
质量水平
100
500
偶联物
unconjugated
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
MMA, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形式
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (115M-14)
vial of 0.5 mL concentrate (115M-15)
bottle of 1.0 mL predilute (115M-17)
vial of 1.0 mL concentrate (115M-16)
bottle of 7.0 mL predilute (115M-18)
制造商/商品名称
Cell Marque™
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同位素/亚型
IgM
控制
Hodgkin lymphoma
运输
wet ice
储存温度
2-8°C
可视化
cytoplasmic, membranous
基因信息
human ... FUT4(2526)
一般描述
A positive reaction for CD15 combined with a negative reaction for LCA and other B and T lineage markers provides support for Reed-Sternberg cells found in Hodgkin′s disease. Also this antibody does not detect mesotheliomas making it a more frequently used antibody to distinguish epithelial mesothelioma from adenocarcinoma.
质量
 IVD |  IVD |  IVD |  RUO |
联系
CD15 Positive Control Slides, Product No. 115S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
法规信息
监管及禁止进口产品
S H Swerdlow et al.
American journal of clinical pathology, 85(3), 283-288 (1986-03-01)
Leu-M1, or MMA, originally was proposed as a differentiation antigen on myelomonocytic cells and was said to be useful as an aid in distinguishing lymphoid from myeloid leukemias. Subsequently, it was proposed by Hsu and Jaffe as a useful marker
G S Pinkus et al.
The American journal of pathology, 119(2), 244-252 (1985-05-01)
Monoclonal antibody to Leu-M1, a granulocyte-related differentiation antigen, represents a highly effective reagent for detection of diagnostic Reed-Sternberg (R-S) cells and variants in paraffin-embedded tissues of Hodgkin's disease. In 69 of 73 cases of Hodgkin's disease (41 nodular sclerosis, 25
K Skubitz, et al.
Leucocyte Typing IV, 800-805 (1989)
R Wieczorek et al.
The American journal of pathology, 121(3), 374-380 (1985-12-01)
The Leu-M1 antigen has been recently proposed as a valuable immunodiagnostic marker of the Reed-Sternberg cells of Hodgkin's disease and to be particularly helpful is distinguishing Hodgkin's disease from other lymphoproliferative disorders such as peripheral T-cell lymphomas. In this study
S M Hsu et al.
American journal of clinical pathology, 82(1), 29-32 (1984-07-01)
It has been suggested that the malignant cells of Hodgkin's disease (HD), Reed-Sternberg cells, and their mononuclear variants may be related to cells of the monocyte-histiocyte system. To test this hypothesis, 20 cases of HD were tested with nine antibodies
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