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About This Item
经验公式（希尔记法）:
C6H14N4O2 · HCl
CAS号:
分子量:
210.66
Beilstein:
3631658
EC 号:
MDL编号:
UNSPSC代码:
12352209
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方案
≥99.0% (AT)
旋光性
[α]20/D +22.0±0.5°, c = 5% in 5 M HCl
杂质
≤0.3% foreign amino acids
灼烧残渣
≤0.1% (as SO4)
缺失
≤0.1% loss on drying
溶解性
H2O: freely soluble
alcohol: slightly soluble (Hot)
痕量阴离子
sulfate (SO42-): ≤50 mg/kg
痕量阳离子
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
SMILES字符串
Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChI key
KWTQSFXGGICVPE-WCCKRBBISA-N
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应用
L-Arginine hydrochloride has been used as a test compound for examining the impact of L-NG-monomethyl arginine (L-NMMA) and L-NG-nitro arginine (L-NOARG) on non-adrenergic, non-cholinergic relaxations of mouse anococcygeus muscle. It has also been used as a standard test compound for investigating whether the absolute concentration of a protein within a mixture of other proteins can be measured with SI traceability.
生化/生理作用
L-Arginine enhances the urine urea excretion and has increased values for glomerular filtration rate (GFR) and P-amino hippurate (PAH) clearance in rats with remnant kidneys.
一氧化氮合成酶的底物，可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
A Gibson et al.
British journal of pharmacology, 99(3), 602-606 (1990-03-01)
1. The effects of L-NG-monomethyl arginine (L-NMMA) and L-NG-nitro arginine (L-NOARG) on non-adrenergic, non-cholinergic (NANC) relaxations of the mouse anococcygeus were investigated. 2. L-NMMA (10-200 microM) produced a concentration-related inhibition of the NANC response; the inhibitory effect of 50 microM
A A Reyes et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 20(2), 168-176 (1992-08-01)
We studied the effect of dietary supplementation with L-arginine for 6 weeks on the progression of renal disease in female Sprague-Dawley rats subjected to sham-operation (groups 1 and 2) or surgical ablation of 85% to 90% of the total renal
Toward Système International d'Unité-traceable protein quantification: from amino acids to proteins.
William I Burkitt et al.
Analytical biochemistry, 376(2), 242-251 (2008-03-14)
Here we present a demonstration of the proof of principle that absolute concentration of a protein within a mixture of other proteins can be measured with SI traceability. The method used was based on tryptic digestion of a protein followed
Nivaldo Ribeiro Villela et al.
Journal of translational medicine, 12, 232-232 (2014-08-26)
Relative hypovolemia is frequently found in early stages of severe sepsis and septic shock and prompt and aggressive fluid therapy has become standard of care improving tissue perfusion and patient outcome. This paper investigates the role of the nitric oxide
Jenna Gallie et al.
PLoS biology, 13(3), e1002109-e1002109 (2015-03-13)
Phenotype switching is commonly observed in nature. This prevalence has allowed the elucidation of a number of underlying molecular mechanisms. However, little is known about how phenotypic switches arise and function in their early evolutionary stages. The first opportunity to
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