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安全信息

108M-9

Sigma-Aldrich

CD8 (C8/144B) Mouse Monoclonal Antibody

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UNSPSC代码:
12352200
NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

diluted ascites fluid

抗体产品类型

primary antibodies

克隆

C8/144B, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (108M-94)
vial of 0.5 mL concentrate (108M-95)
bottle of 1.0 mL predilute (108M-97)
vial of 1.0 mL concentrate (108M-96)
bottle of 7.0 mL predilute (108M-98)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

同位素/亚型

IgG1κ

控制

tonsil

运输

wet ice

储存温度

2-8°C

可视化

membranous

基因信息

human ... CD8A(925)

一般描述

Anti-CD8 is a T cell marker for the detection of cytotoxic/suppresser cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody, along with other markers, can be used to distinguish between reactive and neoplastic T-cells.

质量


IVD

IVD

IVD

RUO

联系

CD8 Positive Control Slides, Product No. 108S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

法规信息

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M L Rossi et al.
Journal of clinical pathology, 41(3), 314-319 (1988-03-01)
Twenty four meningiomas (17 benign and seven "atypical" were reacted with a panel of monoclonal antibodies to macrophages, lymphocytes, and HLA DR antigens. All the tumours contained macrophages but these cells were more numerous in the atypical meningiomas. Lymphocytes, almost
J D Nuckols et al.
Journal of cutaneous pathology, 26(4), 169-175 (1999-05-21)
Differentiation between mycosis fungoides (MF) and cutaneous inflammatory processes can usually be made on clinical and histologic grounds. In difficult cases, immunohistochemical studies can be helpful since MF infiltrates usually contain a predominance of CD4+ lymphocytes, while most inflammatory lesions
D Y Mason et al.
Journal of clinical pathology, 45(12), 1084-1088 (1992-12-01)
To evaluate whether cytotoxic/suppressor T cells can be detected in paraffin wax embedded human tissue samples using antibodies to a synthetic CD8 peptide sequence. Polyclonal and monoclonal antibodies were raised against a 13 amino acid peptide sequence from the cytoplasmic
JAK-STAT activation contributes to cytotoxic T cell-mediated basal cell death in human chronic lung allograft dysfunction.
Khatri, et al.
JCI insight, 8 (2023)

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