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Merck
CN

0710000

Sigma-Aldrich

(4-tert.-Butylphenoxy)-essigsäure

≥98.0% (HPLC)

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别名:
[4-(1,1-Dimethylethyl)phenoxy]-acetic acid
线性分子式:
(CH3)3CC6H4OCH2CO2H
CAS号:
分子量:
208.25
Beilstein:
2368208
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.26

检测方案

≥98.0% (HPLC)

mp

96 °C (lit.)

SMILES字符串

CC(C)(C)c1ccc(OCC(O)=O)cc1

InChI

1S/C12H16O3/c1-12(2,3)9-4-6-10(7-5-9)15-8-11(13)14/h4-7H,8H2,1-3H3,(H,13,14)

InChI key

FBIGAJNVRFKBJL-UHFFFAOYSA-N

应用

Reagent for the TAC protective group in nucleosides

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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N D Sinha et al.
Biochimie, 75(1-2), 13-23 (1993-01-01)
The use of tert-butylphenoxyacetyl for N-protection of nucleoside bases during oligonucleotide synthesis facilitates its removal under mild conditions. This protecting group reduces depurination of deoxyadenosine residues, and minimizes premature desilylation resulting in chain degradation during post-synthesis workup of synthetic RNA.
Katarzyna Przejczowska-Pomierny et al.
Chirality, 29(9), 500-511 (2017-07-06)
A direct fluorometric high-performance liquid chromatography (HPLC) method was developed and validated for the analysis of ibuprofen enantiomers in mouse plasma (100 μl) and tissues (brain, liver, kidneys) using liquid-liquid extraction and 4-tertbutylphenoxyacetic acid as an internal standard. Separation of enantiomers
K E Cole et al.
The Journal of experimental medicine, 187(12), 2009-2021 (1998-06-24)
Chemokines are essential mediators of normal leukocyte trafficking as well as of leukocyte recruitment during inflammation. We describe here a novel non-ELR CXC chemokine identified through sequence analysis of cDNAs derived from cytokine-activated primary human astrocytes. This novel chemokine, referred

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