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Merck
CN

06627

Sigma-Aldrich

2-氨基吖啶酮

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

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别名:
2-氨基-10H-吖啶-9-酮, 2-氨基-9 (10H)-吖啶酮, 美国医学协会
经验公式(希尔记法):
C13H10N2O
CAS号:
分子量:
210.23
Beilstein:
172520
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32

产品线

BioReagent

质量水平

检测方案

≥98.0% (HPLC)

溶解性

DMF: soluble
DMSO: soluble

荧光

λex 420 nm; λem 542 nm in 0.1 M Tris pH 8.0

适用性

suitable for fluorescence

SMILES字符串

Nc1ccc2Nc3ccccc3C(=O)c2c1

InChI

1S/C13H10N2O/c14-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)15-12/h1-7H,14H2,(H,15,16)

InChI key

PIGCSKVALLVWKU-UHFFFAOYSA-N

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应用

2-氨基吖啶酮是一种高度荧光芳香化合物,它含有伯胺基,可与碳水化合物的还原端醛基发生反应,被硼氢化钠还原为稳定的胺衍生物(NaBH4)。 可以利用这个荧光团检测聚糖化合物的皮摩尔水平。所得衍生化合物可用反相高效液相色谱法分离,通过正离子电喷雾质谱法MS检测一种强大的荧光疏水探针,在广泛的 pH 范围内性能稳定,适用于聚糖衍生化,结合胶束电动毛细管色谱、反相和正相色谱结合质谱分析来分析复合寡聚糖,从而测定个别低聚糖的相对浓度和结构同一性。λ激发和λ发射分别为425 nm和532 nm。
聚糖和糖的荧光标记。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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商品

蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时,它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因,它们在细胞表面的表现通常被称为“糖”。

Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.

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