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Merck
CN

02582

Sigma-Aldrich

4-Pyridoxolactone

≥98.5% (HPLC)

别名:

β-Pyracin, 4-Pyridoxic acid lactone, 7-Hydroxy-6-methylfuro[3,4-c]pyridin-1(3H)-one

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About This Item

经验公式(希尔记法):
C8H7NO3
CAS号:
分子量:
165.15
Beilstein:
140752
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.79

方案

≥98.5% (HPLC)
98.5-101.5% (T)

表单

powder

技术

HPLC: suitable

颜色

white to light yellow

储存温度

−20°C

SMILES字符串

O=C1OCC2=CN=C(C)C(O)=C21

InChI

1S/C8H7NO3/c1-4-7(10)6-5(2-9-4)3-12-8(6)11/h2,10H,3H2,1H3

InChI key

HHPDVQLBYQFYFA-UHFFFAOYSA-N

生化/生理作用

4-Pyridoxolactone is a bacterial oxidation metabolite of vitamin B6.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Z Bannur et al.
Clinical biochemistry, 47(6), 427-431 (2014-03-04)
Acute lymphoblastic leukaemia (ALL) has posed challenges to the clinician due to variable patients' responses and late diagnosis. With the advance in metabolomics, early detection and personalised treatment are possible. Metabolomic profile of 21 ALL patients treated with 6-mercaptopurine and
Nana Yokochi et al.
The Journal of biological chemistry, 279(36), 37377-37384 (2004-07-01)
Microbacterium luteolum YK-1 has pyridoxine degradation pathway I. We have cloned the structural gene for the second step enzyme, pyridoxal 4-dehydrogenase. The gene consists of 1,026-bp nucleotides and encodes 342 amino acids. The enzyme was overexpressed under cold shock conditions
Junichi Funami et al.
Biochimica et biophysica acta, 1753(2), 234-239 (2005-10-18)
4-Pyridoxolactonase is involved in the degradation pathway for pyridoxine, a free form of vitamin B6. The gene (mlr6805) encoding the putative 4-pyridoxolactonase of nitrogen fixing symbiotic microorganism Mesorhizobium loti MAFF303099 has been identified based on the genome database. The gene
Saki Nishimura et al.
Journal of nutritional science and vitaminology, 54(1), 18-24 (2008-04-05)
A determination method for individual natural vitamin B(6) compounds was developed. The vitamin B(6) compounds were specifically converted into 4-pyridoxolactone (PAL), a highly fluorescent compound, through a combination of enzymatic reactions and HCl-hydrolysis. PAL was then determined by HPLC. Pyridoxal
Jun Peng et al.
Analytica chimica acta, 803, 97-105 (2013-11-13)
A large fraction of the known human metabolome belong to organic acids. However, comprehensive profiling of the organic acid sub-metabolome is a major analytical challenge. In this work, we report an improved method for detecting organic acid metabolites. This method

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