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关于此项目
线性分子式:
C39H76NO8P
化学文摘社编号:
分子量:
718.00
PubChem Substance ID:
UNSPSC Code:
51191904
NACRES:
NA.85
EC Number:
247-894-0
MDL number:
InChI key
FHQVHHIBKUMWTI-ISLYRVAYSA-N
InChI
1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17+
assay
≥95% (TLC)
form
solid
functional group
amine
lipid type
phosphoglycerides
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
脂质对膜相关疏水螺旋,GRP1 PH结构域靶向膜的形貌的影响。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Ju He et al.
Journal of lipid research, 49(8), 1807-1815 (2008-05-13)
The general receptor for phosphoinositides isoform 1 (GRP1) is recruited to the plasma membrane in response to activation of phosphoinositide 3-kinases and accumulation of phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)]. GRP1's pleckstrin homology (PH) domain recognizes PtdIns(3,4,5)P(3) with high specificity and affinity, however
R Willumeit et al.
Journal of materials science. Materials in medicine, 18(2), 367-380 (2007-02-27)
Bio-interfaces such as bio-membranes are of outmost importance for a variety of live processes. Among them are cell-interactions which take place in, on or through cell membranes. Therefore we propose to cover metallic surfaces with phospholipids to facilitate cell-material interaction.
Khurshida Shahidullah et al.
Journal of molecular biology, 379(4), 704-718 (2008-05-16)
To investigate the effect of lipid structure upon the membrane topography of hydrophobic helices, the behavior of hydrophobic peptides was studied in model membrane vesicles. To define topography, fluorescence and fluorescence quenching methods were used to determine the location of
Hui-Hsu Gavin Tsai et al.
Biochimica et biophysica acta, 1838(6), 1529-1535 (2014-01-29)
Membrane fusion is essential for intracellular trafficking and virus infection, but the molecular mechanisms underlying the fusion process remain poorly understood. In this study, we employed all-atom molecular dynamics simulations to investigate the membrane fusion mechanism using vesicle models which
Sophia C Goodchild et al.
PloS one, 9(8), e104492-e104492 (2014-08-08)
Although the molecular mechanisms underlying the pathology of amyloidoses are not well understood, the interaction between amyloid proteins and cell membranes is thought to play a role in several amyloid diseases. Amyloid fibrils of β2-microglobulin (β2m), associated with dialysis-related amyloidosis
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