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Merck
CN

01991

Sigma-Aldrich

2-油酰-1-棕榈酰-sn-甘油-3-磷酸乙醇胺

≥95% (TLC)

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别名:
1-十六酰基-2-(顺式-9-十八烯酰基)-sn-甘油-3-磷酸乙醇胺, 1-棕榈酰-2-油酰-sn-甘油-3-磷酸乙醇胺, 3-sn-磷脂酰乙醇胺,2-油酰-1-棕榈酰, L-β-油酰-γ-棕榈酰-α-脑磷脂, POPE
线性分子式:
C39H76NO8P
CAS号:
分子量:
718.00
EC 号:
MDL编号:
UNSPSC代码:
51191904
PubChem化学物质编号:
NACRES:
NA.85

质量水平

检测方案

≥95% (TLC)

形式

solid

官能团

amine

脂质类型

phosphoglycerides

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C\CCCCCCCC

InChI

1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17+

InChI key

FHQVHHIBKUMWTI-ISLYRVAYSA-N

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生化/生理作用

脂质对膜相关疏水螺旋,GRP1 PH结构域靶向膜的形貌的影响。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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R Willumeit et al.
Journal of materials science. Materials in medicine, 18(2), 367-380 (2007-02-27)
Bio-interfaces such as bio-membranes are of outmost importance for a variety of live processes. Among them are cell-interactions which take place in, on or through cell membranes. Therefore we propose to cover metallic surfaces with phospholipids to facilitate cell-material interaction.
Ju He et al.
Journal of lipid research, 49(8), 1807-1815 (2008-05-13)
The general receptor for phosphoinositides isoform 1 (GRP1) is recruited to the plasma membrane in response to activation of phosphoinositide 3-kinases and accumulation of phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P(3)]. GRP1's pleckstrin homology (PH) domain recognizes PtdIns(3,4,5)P(3) with high specificity and affinity, however
Khurshida Shahidullah et al.
Journal of molecular biology, 379(4), 704-718 (2008-05-16)
To investigate the effect of lipid structure upon the membrane topography of hydrophobic helices, the behavior of hydrophobic peptides was studied in model membrane vesicles. To define topography, fluorescence and fluorescence quenching methods were used to determine the location of
Hui-Hsu Gavin Tsai et al.
Biochimica et biophysica acta, 1838(6), 1529-1535 (2014-01-29)
Membrane fusion is essential for intracellular trafficking and virus infection, but the molecular mechanisms underlying the fusion process remain poorly understood. In this study, we employed all-atom molecular dynamics simulations to investigate the membrane fusion mechanism using vesicle models which
Y Murakami et al.
Cell death and differentiation, 21(11), 1746-1757 (2014-07-19)
The CD300 receptor family members are a group of molecules that modulate a variety of immune cell processes. We show that mouse CD300b (CLM7/LMIR5), expressed on myeloid cells, recognizes outer membrane-exposed phosphatidylserine (PS) and does not, as previously reported, directly

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