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蒸汽密度
3.5 (vs air)
质量水平
蒸汽压
70 mmHg ( 25 °C)
产品线
ReagentPlus®
方案
≥99%
表单
liquid
自燃温度
~896 °F
expl. lim.
42 %
折射率
n20/D 1.3 (lit.)
pH值(酸碱度)
7
沸点
77-80 °C (lit.)
mp
−44 °C (lit.)
密度
1.373 g/mL at 25 °C (lit.)
SMILES字符串
OCC(F)(F)F
InChI
1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
InChI key
RHQDFWAXVIIEBN-UHFFFAOYSA-N
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一般描述
2,2,2-三氟乙醇(TFE)是一种有机化合物,化学式为 CF3CH2OH。TFE 是有机合成中常用的溶剂。它也可以用作蛋白质和多肽实验研究中的助溶剂。
应用
2,2,2-三氟乙醇可作为溶剂:
- 通过醛、丙二腈和间苯二酚或二美酮的无催化剂一锅缩合合成 2-氨基-3-氰基-4H-铬和四氢苯[b]吡喃衍生物。
- 在异相 ZIF-8(沸石咪唑酸框架)催化剂环境下,氨基与甲酸的 N-甲酰化。
- 通过蒽酰胺与烷基、芳基或杂芳基酮或醛的缩合制备 2-取代-2,3-二氢-4(1H)-喹唑啉酮衍生物。
- 用 H2O2(过氧化氢)对含硫化合物进行温和的选择性氧化。
特点和优势
由于电负性的三氟甲基的存在,2,2,2-三氟乙醇的酸性高于乙醇。
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation
靶器官
Blood
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
86.0 °F - closed cup
闪点(°C)
30 °C - closed cup
法规信息
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