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蒸汽密度
3.1 (20 °C, vs air)
质量水平
蒸汽压
48 mmHg ( 20 °C)
产品线
ReagentPlus®
方案
≥99%
表单
liquid
自燃温度
396 °F
expl. lim.
10.4 %
杂质
≤0.5% (water)
折射率
n20/D 1.379 (lit.)
pH值(酸碱度)
7
沸点
85 °C (lit.)
mp
−58 °C (lit.)
密度
0.867 g/mL at 25 °C (lit.)
SMILES字符串
COCCOC
InChI
1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3
InChI key
XTHFKEDIFFGKHM-UHFFFAOYSA-N
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一般描述
1,2-二甲氧基乙烷(DME)是一种惰性非质子极性溶剂,用于锂电池、聚有机硅、低聚物和多糖的电解质。
应用
1,2-二甲氧基乙烷可作为溶剂合成:
- 恶唑,通过 Robinson-Gabriel 反应从α-酰基胺酮中得到。
- 5-芳基组氨酸,通过 5-溴组氨酸和芳基硼酸之间的 Suzuki-Miyaura 交联。
- 芳基硫醚,通过 Pd-催化芳基卤化物与脂肪和芳香硫醇的硫醚化反应。
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险分类
Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2
补充剂危害
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
41.0 °F - closed cup
闪点(°C)
5 °C - closed cup
法规信息
危险化学品
Organometallics, 13, 1498-1498 (1994)
Tetrahedron Letters, 34, 4591-4591 (1993)
Inorganic Chemistry, 33, 1685-1685 (1994)
Bioresource technology, 129, 667-671 (2013-01-10)
Glymes (i.e. glycol diethers) were explored as alternative benign solvents for enzymatic reactions, specifically the lipase-catalyzed transesterification. Long-chain glymes were found highly compatible with immobilized Candida antarctica lipase B (iCALB), leading to higher enzyme activities and stabilities than t-butanol and
Ophthalmology, 122(3), 545-554 (2014-12-03)
AKB-9778 is a small-molecule competitive inhibitor of vascular endothelial-protein tyrosine phosphatase (VE-PTP) that promotes Tie2 activation and reduces vascular leakage and neovascularization in mouse models. The purpose of this study was to test the safety, tolerability, pharmacokinetics, and biological activity
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